PMID: 16518284Mar 7, 2006Paper

Trends in incidence and management of esophageal adenocarcinoma in a well-defined population

Gastroentérologie Clinique Et Biologique
Côme LepageJ Faivre

Abstract

Little epidemiological data is available concerning esophageal adenocarcinomas in France. The aim of this study was to study epidemiological characteristics and management of esophageal adenocarcinoma in a well-defined population. Data were collected by the Burgundy Digestive Cancer Registry covering a population of 1 052 000, over a 28-year period (1976-2001). Incidence, treatment and stage at diagnosis were noted. Univariate and multivariate analysis of survival was performed. Age standardized incidence rates were 1.60/100,000 in men and 0.15/100,000 in women. The mean increase in incidence rates by 5-year periods were respectively + 68.1% (P<0.001) and + 97.4% (P<0.001). Overall, 69.9% of the cancers were located in the lower third of the esophagus. Surgical resection was performed in 32.1% of patients. Among the surgical patients, the tumor was limited to the esophageal wall in 11.4%, lymph node metastases were present in 18.1% and non-resectable distant metastases in 70.5%. There was no improvement of stage at diagnosis over time. Survival rates were 14.4% at 3 years and 9.2% at 5 years. Five-year survival rates varied from 38.4% for cases limited to the esophageal wall to 1.8% for metastatic and non resectable cases. Stag...Continue Reading

References

Mar 23, 1991·JAMA : the Journal of the American Medical Association·W J BlotJ F Fraumeni
Sep 1, 1990·British Journal of Cancer·J Powell, C C McConkey
May 28, 1993·International Journal of Cancer. Journal International Du Cancer·L E HanssonO Nyrén
Aug 15, 1996·The New England Journal of Medicine·T N WalshT P Hennessy
Sep 18, 1997·Journal of the National Cancer Institute·M D GammonJ F Fraumeni
Jul 4, 1998·International Journal of Radiation Oncology, Biology, Physics·S J ArnottZ Rugang
Jun 26, 1998·Journal of Gastroenterology and Hepatology·R V LordV Thursfield
Dec 31, 1998·The New England Journal of Medicine·D P KelsenJ A Roth
Feb 6, 1999·The American Journal of Gastroenterology·P BytzerN Seersholm
Aug 3, 2000·International Journal of Epidemiology·A A BotterweckP A van Den Brandt
Mar 27, 2001·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·F LeviC La Vecchia
May 1, 2002·European Journal of Gastroenterology & Hepatology·Bas P L WijnhovenJan-Willem W Coebergh
Jun 7, 2002·Lancet·UNKNOWN Medical Research Council Oesophageal Cancer Working Group
Jul 13, 2002·International Journal of Cancer. Journal International Du Cancer·A Paloma VizcainoD Maxwell Parkin
Apr 3, 2003·International Journal of Cancer. Journal International Du Cancer·Anthony P Polednak
Jul 23, 2003·The American Journal of Gastroenterology·Mohamad A EloubeidiHashem B El-Serag
Sep 18, 2003·Journal of the National Cancer Institute·Lawrence S EngelJoseph F Fraumeni

❮ Previous
Next ❯

Citations

Jul 1, 2011·Journal of Visceral Surgery·D TougeronC Silvain
Mar 5, 2013·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Côme LepageJean Faivre
Oct 16, 2008·The American Journal of Gastroenterology·Côme LepageMichel P Coleman
Dec 20, 2007·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·Côme LepageUNKNOWN French network of cancer registries (FRANCIM)

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The New England Journal of Medicine
Peter C Enzinger, Robert J Mayer
European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
Christophe MarietteJ P Triboulet
Journal of Surgical Oncology
Matthew R Bower, Robert C G Martin
© 2021 Meta ULC. All rights reserved