Trends in Incidence of Methicillin-resistant Staphylococcus aureus Bloodstream Infections Differ by Strain Type and Healthcare Exposure, United States, 2005-2013

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
Isaac SeeAlexander J Kallen

Abstract

Previous reports suggested that US methicillin-resistant Staphylococcus aureus (MRSA) strain epidemiology has changed since the rise of USA300 MRSA. We describe invasive MRSA trends by strain type. Data came from 5 Centers for Disease Control and Prevention Emerging Infections Program sites conducting population-based surveillance and collecting isolates for invasive MRSA (ie, from normally sterile body sites), 2005-2013. MRSA bloodstream infection (BSI) incidence per 100 000 population was stratified by strain type and epidemiologic classification of healthcare exposures. Invasive USA100 vs USA300 case characteristics from 2013 were compared through logistic regression. From 2005 to 2013, USA100 incidence decreased most notably for hospital-onset (6.1 vs 0.9/100 000 persons, P < .0001) and healthcare-associated, community-onset (10.7 vs 4.9/100 000 persons, P < .0001) BSIs. USA300 incidence for hospital-onset BSIs also decreased (1.5 vs 0.6/100 000 persons, P < .0001). However, USA300 incidence did not significantly change for healthcare-associated, community-onset (3.9 vs 3.3/100 000 persons, P = .05) or community-associated BSIs (2.5 vs 2.4/100 000 persons, P = .19). Invasive MRSA was less likely to be USA300 in patients who...Continue Reading

References

Mar 5, 1998·JAMA : the Journal of the American Medical Association·B C HeroldR S Daum
Dec 11, 2003·JAMA : the Journal of the American Medical Association·Timothy S NaimiRuth Lynfield
Apr 9, 2005·The New England Journal of Medicine·Scott K FridkinUNKNOWN Active Bacterial Core Surveillance Program of the Emerging Infections Program Network
Feb 1, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Ulrich SeyboldHenry M Blumberg
Aug 18, 2006·The New England Journal of Medicine·Gregory J MoranUNKNOWN EMERGEncy ID Net Study Group
Feb 20, 2009·JAMA : the Journal of the American Medical Association·Deron C BurtonScott K Fridkin
Mar 27, 2009·Journal of Clinical Microbiology·Brandi LimbagoUNKNOWN Active Bacterial Core surveillance MRSA Investigators
Mar 30, 2010·Journal of Pain & Palliative Care Pharmacotherapy· U S Food And Drug Administration
Aug 12, 2010·JAMA : the Journal of the American Medical Association·Alexander J KallenUNKNOWN Active Bacterial Core surveillance (ABCs) MRSA Investigators of the Emerging Infections Program
Aug 12, 2010·JAMA : the Journal of the American Medical Association·Eli N Perencevich, Daniel J Diekema
Apr 15, 2011·The New England Journal of Medicine·Rajiv JainGary A Roselle
May 9, 2013·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Matthew E WiseJohn A Jernigan
Feb 14, 2014·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Daniel J DiekemaGary V Doern
Mar 5, 2014·Antimicrobial Agents and Chemotherapy·Katie J SudaThomas H Taylor
Jun 1, 2014·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Michael Z DavidBrad Spellberg
Oct 8, 2014·JAMA : the Journal of the American Medical Association·Shelley S MagillUNKNOWN Emerging Infections Program Healthcare-Associated Infections and Antimicrobial Use Prevalence Survey Team
Jul 15, 2015·The New England Journal of Medicine·Seema JainUNKNOWN CDC EPIC Study Team
Sep 16, 2015·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Yoona RheeKyle J Popovich
Oct 22, 2016·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Lindsey M WeinerDawn M Sievert
Apr 5, 2017·The Journal of Infectious Diseases·Paul J Planet
Nov 3, 2017·Journal of Clinical Microbiology·Sanjat KanjilalYonatan H Grad

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Citations

Jun 4, 2020·Journal of Aging & Social Policy·Jeffrey E Stokes, Sarah E Patterson
May 21, 2020·The Journal of Infectious Diseases·Jennifer L GuthrieUNKNOWN Ontario CNISP Hospital Investigators
Feb 13, 2020·Intensive Care Medicine·Jean-François TimsitMatteo Bassetti
Apr 4, 2020·The New England Journal of Medicine·John A JerniganJames Baggs
Apr 4, 2020·The New England Journal of Medicine·Ferric C Fang, Robert T Schooley
Dec 17, 2021·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Gabrielle M GussinSusan S Huang

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