Trends in major entry site complications from percutaneous coronary intervention (from the Dynamic Registry)

The American Journal of Cardiology
Kristal YoungJ Dawn Abbott

Abstract

Several factors contribute to the risk of percutaneous coronary intervention-related major entry site (MES) complications. We sought to examine the trends in MES among unselected patients during the stent era. Data from the Dynamic Registry including 5 distinct recruitment waves from 1997 to 2006 (n = 10,932) were used to assess baseline characteristics and MES among consecutive patients undergoing percutaneous coronary intervention. MES was defined as bleeding requiring transfusion, pseudoaneurysm, arterial thrombosis or dissection, vascular complication requiring surgery, or retroperitoneal bleed. Uncomplicated hematomas were not included. Several trends were observed in baseline characteristics including an increase from wave 1 to wave 5 in body mass index >30 kg/m(2) (30.2% to 40.4%), renal disease (3.5% to 9.1%), diabetes (28.0% to 34.1%), and hypertension (59.4% to 78%; ptrend <0.001 for all). The use of a thienopyridine increased significantly from wave 1 (49.7%) to wave 5 (84%), whereas glycoprotein IIb/IIIa inhibitor use peaked in wave 3 (53.1%) and then decreased (p <0.001). Access site was predominately femoral, but radial access increased over time (0.3% wave 1, 6.6% wave 5, p ≤0.0001). The rates of MES (2.8% to 2.2...Continue Reading

References

Jun 11, 2003·American Heart Journal·Winthrop D PiperUNKNOWN Northern New England Cardiovascular Disease Study Group
Oct 7, 2004·JAMA : the Journal of the American Medical Association·Sunil V RaoRobert M Califf
Aug 16, 2006·Circulation·John W EikelboomSalim Yusuf
May 24, 2008·The New England Journal of Medicine·Gregg W StoneUNKNOWN HORIZONS-AMI Trial Investigators
Dec 25, 2009·Circulation. Cardiovascular Interventions·Lakshmi VenkitachalamUNKNOWN Investigators of NHLBI-Sponsored 1985-1986 PTCA and 1997-2006 Dynamic Registries
Jun 3, 2010·JAMA : the Journal of the American Medical Association·Steven P MarsoUNKNOWN National Cardiovascular Data Registry
Jul 17, 2010·Journal of the American College of Cardiology·Matthew T RoeJohn S Rumsfeld
Oct 30, 2012·Journal of the American College of Cardiology·Shamir R MehtaUNKNOWN RIVAL Investigators
Jul 25, 2013·Circulation. Cardiovascular Interventions·Gjin NdrepepaAdnan Kastrati

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Citations

Jun 9, 2016·Journal of cardiology·Yohei NumasawaKeiichi Fukuda
May 23, 2014·Expert Review of Cardiovascular Therapy·Giuseppe VergaroAndrea Del Corso
Oct 8, 2020·European Heart Journal. Acute Cardiovascular Care·Christian DworeckElmir Omerovic

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