Trends in management and outcomes of ST-elevation myocardial infarction in patients with end-stage renal disease in the United States

The American Journal of Cardiology
Tanush GuptaWilbert S Aronow

Abstract

Acute myocardial infarction in patients with end-stage renal disease (ESRD) is associated with increased risk of morbidity and mortality. Limited data are available on the contemporary trends in management and outcomes of ST-elevation myocardial infarction (STEMI) in patients with ESRD. We analyzed the 2003 to 2011 Nationwide Inpatient Sample databases to examine the temporal trends in STEMI, use of mechanical revascularization for STEMI, and in-hospital outcomes in patients with ESRD aged ≥18 years in the United States. From 2003 to 2011, whereas the number of patients with ESRD admitted with the primary diagnosis of acute myocardial infarction increased from 13,322 to 20,552, there was a decrease in the number of STEMI hospitalizations from 3,169 to 2,558 (ptrend <0.001). The overall incidence rate of cardiogenic shock in patients with ESRD and STEMI increased from 6.6% to 18.3% (ptrend <0.001). The use of percutaneous coronary intervention for STEMI increased from 18.6% to 37.8% (ptrend <0.001), whereas there was no significant change in the use of coronary artery bypass grafting (ptrend = 0.32). During the study period, in-hospital mortality increased from 22.3% to 25.3% (adjusted odds ratio [per year] 1.09; 95% confidence ...Continue Reading

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Citations

Apr 26, 2015·The American Journal of Medicine·Tanush GuptaJulio A Panza
Jul 7, 2016·The American Journal of Cardiology·Tanush GuptaJulio A Panza
Jun 25, 2017·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Abhinav GoyalJanani Rangaswami
Jun 18, 2015·Journal of the American Heart Association·Tanush GuptaJulio A Panza
Oct 22, 2019·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Homam Moussa PachaM Chadi Alraies
May 31, 2020·Journal of Nephrology·Alexandru BurlacuUNKNOWN EUDIAL Working Group of ERA-EDTA

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