Trends in microbiological spectrum of endophthalmitis at a single tertiary care ophthalmic hospital in India: a review of 25 years

Eye
Joveeta JosephTaraprasad Das

Abstract

To determine trends in the microbial spectrum of endophthalmitis over the past 25 years and to review its antibiotic susceptibility patterns over the last 10 years. Microbiology records of culture-positive endophthalmitis cases from 1991 to 2015 were reviewed. Additionally, data between 2005 and 2015 was also analyzed for trends in antibiotic susceptibility. Of the total of 9278 patients, 3319 (35.7%) were culture positive and included bacteria (2840/3319, 85.56%), fungi (387/3319, 11.66%), and mixed cultures (92/3319, 2.7%). Gram-positive bacteria accounted for 67.68% (1922/2840) of the total bacteria seen, with the most prevalent pathogen being Streptococcus pneumoniae and Staphylococcus epidermidis. Among the gram-negative organisms Pseudomonas aeruginosa was the most prevalent while. Aspergillus flavus was the most common fungus isolated and Candida sp. accounted for 6.9% of the total fungi isolated. There was no significant change in the trends of bacteria isolated during the study period. Overall susceptibility patterns showed that gram-positive bacteria were most susceptible to vancomycin (96%) and fluoroquinolones (89%). The resistance to ceftazidime increased from 31% in 2005 to 62% in 2015 (P = 0.006) and amikacin dec...Continue Reading

References

Jul 1, 1996·American Journal of Ophthalmology·D P HanS F Kelsey
Nov 1, 1996·Ophthalmology·I U ScottD Miller
Jan 10, 2002·Clinical Microbiology Reviews·Michelle C CalleganMichael S Gilmore
Jul 10, 2003·Survey of Ophthalmology·Timothy L JacksonMiles R Stanford
Apr 15, 2005·Indian Journal of Ophthalmology·Taraprasad DasUNKNOWN Endophthalmitis Research Group
Feb 27, 2013·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·M L Durand
Jun 21, 2017·Indian Journal of Pathology & Microbiology·Gita SatpathyVishnu Sreenivas

❮ Previous
Next ❯

Citations

Jan 15, 2020·Asia-Pacific Journal of Ophthalmology·Taraprasad Das
Jul 9, 2020·Clinical & Experimental Ophthalmology·Gursimrat K BhullarPenelope J Allen
Sep 18, 2020·Investigative Ophthalmology & Visual Science·Bruce G RottmannAshok Kumar
Jan 29, 2020·Asia-Pacific Journal of Ophthalmology·Taraprasad Das
Aug 19, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Yao YangXiaofeng Lin
Jun 27, 2020·Indian Journal of Ophthalmology·Taraprasad Das
Jan 5, 2021·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Hiroshi EguchiShunji Kusaka
Feb 8, 2021·Experimental Eye Research·Konduri RanjithSisinthy Shivaji
Nov 23, 2021·Ocular Immunology and Inflammation·Kushal Umeshbhai AgrawalMaikel Gad

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bacterial Pneumonia (ASM)

Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.

Aminoglycosides

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Bacterial Pneumonia

Bacterial pneumonia is a prevalent and costly infection that is a significant cause of morbidity and mortality in patients of all ages. Here is the latest research.

Aminoglycosides (ASM)

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Related Papers

Current Clinical Topics in Infectious Diseases
M L Durand, J S Heier
Klinische Monatsblätter für Augenheilkunde
W Behrens-Baumann
© 2022 Meta ULC. All rights reserved