Trends in Oral Antibiotic, Proton Pump Inhibitor, and Histamine 2 Receptor Blocker Prescription Patterns for Children Compared With Adults: Implications for Clostridium difficile Infection in the Community

Clinical Pediatrics
Howard S Faden, Chan-Xing Ma

Abstract

The use of antibiotics, proton pump inhibitor (PPI), and histamine 2 receptor blocker (H2B) was compared between children and adults in the community from 2005 through 2011. Antibiotic prescription rates remained stable for children, but increased significantly for adults, P = .03. PPI prescription rates increased for children, P = .02 and for adults, P = .009. H2B prescription rates increased for children, P = .03, but not for adults. Antibiotic prescription rates were significantly higher in children than adults in all 7 years, P < .0001. In contrast, PPI prescription rates were significantly higher in adults than children in all 7 years, P < .0001. H2B prescription rates were significantly higher in adults than children 1 to 18 years old P < .0001; however, H2B prescription rates were highest in children <1 year old, P = .0001. The high use of oral antibiotics, PPI, and H2B among outpatients may be a contributing factor to the rise of Clostridium difficile infection in the community.

References

Jun 19, 2002·JAMA : the Journal of the American Medical Association·Linda F McCaigJames M Hughes
Feb 20, 2004·Pharmacoepidemiology and Drug Safety·Gregory S CooperSiran M Koroukian
Jan 18, 2006·JAMA : the Journal of the American Medical Association·Sandra DialSamy Suissa
Nov 22, 2007·Journal of Pediatric Gastroenterology and Nutrition·John J BarronJoseph Singer
Jan 6, 2010·Alimentary Pharmacology & Therapeutics·R TurcoA Staiano
Jun 10, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Vanessa StevensEdwin van Wijngaarden
Apr 25, 2012·The American Journal of Gastroenterology·Chun Shing KwokYoon Kong Loke
Jun 20, 2012·The American Journal of Gastroenterology·Sailajah JanarthananMurray N Ehrinpreis
Jun 27, 2012·Pediatrics·Sharon K GreeneJonathan A Finkelstein
Feb 4, 2014·Pediatrics·Louise Elaine VazJonathan A Finkelstein

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Citations

Mar 31, 2016·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·James R JohnsonEvgeni Sokurenko
Oct 4, 2016·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·A Lo VecchioA Guarino
Sep 7, 2018·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Sharon Y IrvingUNKNOWN American Society for Parenteral and Enteral Nutrition
Mar 19, 2019·JAMA Pediatrics·Elaine Barfield, Michelle W Parker
Feb 14, 2018·Neonatal Network : NN·Sara E Rostas, Christopher McPherson
Nov 14, 2019·The Journal of Pediatric Pharmacology and Therapeutics : JPPT : the Official Journal of PPAG·Naomi R M SchwartzAmanda I Phipps
Jun 9, 2019·Pediatrics·Laura MalchodiElizabeth Hisle-Gorman

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