Trends in receiving chemotherapy for advanced cancer patients at the end of life

BMC Palliative Care
Hee Seung LeeSooHyeon Lee

Abstract

The use of chemotherapy in advanced cancer patients has increased with the development of novel, high-efficacy anticancer therapeutic agents. In the current study, we analyzed the 10-year trends in patients receiving chemotherapy at the end of life. We retrospectively reviewed mortality data for advanced cancer patients who died in 2000, 2005, and 2010 at a single institution. The trends of receiving palliative chemotherapy at the end of life were assessed for each year. In addition, logistic regression analysis was performed to determine the factors associated with receiving chemotherapy. We analyzed the records of 2,345 patients who died of cancer. Patients with less responsive tumors were less likely to receive chemotherapy than patients with responsive tumors at the time of death. Patients who were ≥ 65 years were less likely to receive chemotherapy compared with patients who were < 65 years at the end of life. However, the proportion of older patients receiving chemotherapy in the last month of life increased in 2010 (44.2%) compared with 2005 (32.7%) and 2000 (25.7%). Compared with the year 2000, the likelihood of receiving chemotherapy during the last 1 month of life increased in 2005 (odds ratio [OR], 2.05; 95% confiden...Continue Reading

References

Mar 15, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Craig C EarleSusan Block
Apr 16, 2003·Annals of Internal Medicine·Ezekiel J EmanuelArlene S Ash
Jul 18, 2003·The American Journal of Medicine·Quyen Ngo-MetzgerRussell S Phillips
Jan 15, 2004·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Craig C EarleJane C Weeks
Apr 16, 2008·Japanese Journal of Clinical Oncology·Bhumsuk KeamDae Seog Heo
Aug 9, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Craig C EarleJohn Z Ayanian
Sep 4, 2008·Annals of Oncology : Official Journal of the European Society for Medical Oncology·S T TangT-W Liu
Nov 28, 2008·Clinical Colorectal Cancer·Daniel RenoufSharlene Gill
May 27, 2009·Annals of Oncology : Official Journal of the European Society for Medical Oncology·S KaoD Adams
Sep 8, 2010·The New England Journal of Medicine·Jennifer S TemelThomas J Lynch
Mar 16, 2011·Annals of Oncology : Official Journal of the European Society for Medical Oncology·U NäppäB Axelsson
Jan 31, 2012·Acta Oncologica·Tsang-Wu LiuSiew Tzuh Tang
May 18, 2012·Current Pharmaceutical Design·Bradley J MonkAdnan Tanović
Aug 4, 2012·Current Medicinal Chemistry·C S MatosM P M Marques
Mar 15, 2013·The Lancet Oncology·Kathryn Senior

❮ Previous
Next ❯

Citations

Nov 26, 2015·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Wing-lok ChanKwok-keung Yuen
Sep 24, 2015·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Tarek AssiJoseph Kattan
Mar 30, 2017·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Brice ChanezJean-Luc Raoul
Jun 1, 2017·Acta Oncologica·Liisa K RautakorpiSirkku M Jyrkkiö
Mar 14, 2018·The American Journal of Hospice & Palliative Care·Zhe ZhangWen-Wu Cheng
Jul 15, 2017·Cancer Research and Treatment : Official Journal of Korean Cancer Association·Shin Hye YooDae Seog Heo
Apr 2, 2016·Current Treatment Options in Oncology·Divya ChandrasekarKavitha Ramchandran
Aug 2, 2017·Journal of Oncology Practice·Jeffrey T BruckelBrahmajee K Nallamothu
Sep 2, 2019·BMJ Supportive & Palliative Care·Olivier BylickiChristos Chouaid
Sep 4, 2019·Cancer Research and Treatment : Official Journal of Korean Cancer Association·Hyun Jung JhoSun Young Kim
Jul 18, 2020·JCO Oncology Practice·Fauzia RiazCary P Gross
Jun 13, 2019·The American Journal of Hospice & Palliative Care·Rupak DattaManisha Juthani-Mehta
Oct 29, 2020·The American Journal of Hospice & Palliative Care·Lee Ann Johnson, Charles Ellis
May 16, 2020·Clinics and Research in Hepatology and Gastroenterology·Lola-Jade PalmieriSolène Doat
Feb 1, 2020·Medical Hypotheses·Chen ChuXiaochun Zhang
May 1, 2021·Clinics and Research in Hepatology and Gastroenterology·Alexandra Lapeyre-ProstJulien Taieb

❮ Previous
Next ❯

Software Mentioned

SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

HPB : the Official Journal of the International Hepato Pancreato Biliary Association
Erin E BurkeEric H Jensen
Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association
Fahad SaeedAdnan I Qureshi
European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies
S AslanyanK R Lees
© 2021 Meta ULC. All rights reserved