As part of an investigation into the recent epidemic of deaths from asthma in New Zealand, trends in the sales of drugs for asthma in New Zealand, Australia, and the United Kingdom during 1975-81 were examined. Data on sales of drugs were obtained from an international pharmaceutical market research organisation. A striking increase in sales of sympathomimetic aerosols, steroid aerosols, and theophylline per caput occurred in all three countries, with the greatest increase occurring in New Zealand. Sales of sodium cromoglycate also increased in New Zealand and the UK but fell in Australia. By 1981 New Zealand had the highest sales of all these drugs per caput. Explanations for the rising mortality from asthma in New Zealand despite large increases in drug sales need to be explored. Although the temporal association between mortality and sales of drugs suggests that direct drug toxicity is unlikely, there may be more subtle adverse effects of drug use.
A survey of asthma mortality in patients between ages 35 and 64 in the Greater London hospitals in 1971
Could isoenzyme-selective phosphodiesterase inhibitors render bronchodilator therapy redundant in the treatment of bronchial asthma?
Deaths from asthma in Italy (1974-1988): is there a relationship with changing pharmacological approaches?
International trends in sales of inhaled fenoterol, all inhaled beta-agonists, and asthma mortality, 1970-1992
An evaluation of a nurse-run asthma clinic in general practice using an attitudes and morbidity questionnaire
Differences in utilization of asthma drugs between two neighbouring Swedish provinces: relation to treatment in individuals with airway disease
Changes in hospital management of acute severe asthma by thoracic and general physicians in Birmingham and Manchester during 1978 and 1985
Prevalence of asthma among 12 year old children in New Zealand and South Wales: a comparative survey
Total population survey of the frequency and severity of asthma in 17 year old boys in an urban area in Israel
Major reduction in asthma morbidity and continued reduction in asthma mortality in New Zealand: what lessons have been learned?
Nedocromil sodium and placebo in the treatment of bronchial asthma. A multicenter, double-blind, parallel-group comparison
Inflammation and bronchial hyperresponsiveness in allergic asthma and chronic obstructive pulmonary disease
Decrease in asthma mortality rate in Israel from 1991-1995: is it related to increased use of inhaled corticosteroids?
Phosphodiesterase 4 inhibitors and the treatment of asthma: where are we now and where do we go from here?
Evaluation of a program for asthmatic children treated in primary care outpatient units in Embu, São Paulo, 1988-1993
This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.
Allergy and Asthma
Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.