Trends in self-poisoning and psychotropic drug use in people aged 5-19 years: a population-based retrospective cohort study in Australia

BMJ Open
Rose CairnsNicholas A Buckley

Abstract

To characterise trends in self-poisoning and psychotropic medicine use in young Australians. Population-based retrospective cohort study. Calls taken by the New South Wales and Victorian Poisons Information Centres (2006-2016, accounting for 70% of Australian poisoning calls); medicine dispensings in the 10% sample of Australian Pharmaceutical Benefits Scheme data (July 2012 to June 2016). People aged 5-19 years. Yearly trends in intentional poisoning exposure calls, substances taken in intentional poisonings, a prevalence of psychotropic use (dispensing of antidepressants, antipsychotics, benzodiazepines and medicines for attention deficit hyperactivity disorder (ADHD)). There were 33 501 intentional poisonings in people aged 5-19 years, with an increase of 8.39% per year (95% CI 6.08% to 10.74%, p<0.0001), with a 98% increase overall, 2006-2016. This effect was driven by increased poisonings in those born after 1997, suggesting a birth cohort effect. Females outnumbered males 3:1. Substances most commonly taken in self-poisonings were paracetamol, ibuprofen, fluoxetine, ethanol, quetiapine, paracetamol/opioid combinations, sertraline and escitalopram. Psychotropic dispensing also increased, with selective serotonin reuptake i...Continue Reading

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Citations

Mar 7, 2020·European Journal of Public Health·Anita J TørmoenIngeborg Rossow
Jul 28, 2020·Pharmacoepidemiology and Drug Safety·Alexandra G HopkinsGary A Smith
Aug 29, 2020·International Journal of Environmental Research and Public Health·Caroline DalyElla Arensman
Nov 4, 2020·Archives of Disease in Childhood·Jennifer LyRose Cairns
Feb 16, 2021·Journal of Paediatrics and Child Health·Michael A DownesGeoffrey K Isbister
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Jun 15, 2021·Emergency Medicine Australasia : EMA·Andrew K CroftonKatherine Z Isoardi
Jul 3, 2021·International Journal of Environmental Research and Public Health·Samantha PawerIan Pike
Apr 19, 2020·Pediatric Emergency Care·Elaine Yiling TayElizabeth Huiwen Tham

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