Trends in the indication and method of liver biopsy for hepatitis B and C.

Digestive Diseases and Sciences
Michael J LippAlbert D Min

Abstract

Liver biopsy plays a crucial role in assessing inflammation and fibrosis in chronic hepatitis. The aim of this study was to compare the indications and methods for performing a liver biopsy over a 15-year period when there were evolving strategies and increasing therapeutic options for the treatment for chronic hepatitis B (HBV) and C (HCV). We reviewed all percutaneous liver biopsies performed at our center from 1992 to 2007 using a pathology database. Variables collected included indication for biopsy, use of real-time ultrasound (US) guidance, and complications associated with the biopsy. A total of 3,572 total liver biopsies were performed between 1992 and 2007 with a gradual increase in annual liver biopsies from 1992 to 2001. After a peak in 2003, there was a gradual decline in liver biopsies performed. The number of liver biopsies done for HCV peaked in 2003, followed by an annual decrease until 2006, while the number of annual biopsies done for HBV increased during the same period. In addition, the proportion of liver biopsies performed with real-time US-guidance increased steadily since 1997. Changes in liver biopsy trends at our center may be related to several factors, including the evolving treatment strategies for ...Continue Reading

References

Nov 24, 1999·The American Journal of Gastroenterology·T R Riley
Dec 4, 2001·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·A S LokUNKNOWN Practice Guidelines Committee, American Association for the Study of Liver Diseases
Jun 25, 2002·Journal of Clinical Gastroenterology·Andrew J Muir, James F Trotter
Jul 4, 2002·The American Journal of Gastroenterology·Terence L AngtuacoColin W Howden
Sep 27, 2002·The New England Journal of Medicine·Michael W FriedJian Yu
Mar 16, 2004·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Emmet B KeeffeTeresa L Wright
Apr 2, 2004·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Doris B StraderUNKNOWN American Association for the Study of Liver Diseases
Jul 8, 2005·Journal of Clinical Gastroenterology·Harinath SheelaDhanpat Jain
Jan 30, 2007·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Anna S F Lok, Brian J McMahon
May 9, 2007·Gastroenterology·UNKNOWN American Association for the Study of Liver DiseasesUNKNOWN American Society for Gastrointestinal Endoscopy
Oct 9, 2007·Liver International : Official Journal of the International Association for the Study of the Liver·Bandar Al Knawy, Mitchell Shiffman
Oct 12, 2007·Journal of Hepatology·Michelle LaiNezam H Afdhal
Jun 6, 2008·World Journal of Gastroenterology : WJG·Ioan SporeaRoxana Sirli
Oct 11, 2008·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Emmet B KeeffeHillel Tobias
Feb 27, 2009·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Don C RockeyUNKNOWN American Association for the Study of Liver Diseases
Aug 29, 2009·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Anna S F Lok, Brian J McMahon

❮ Previous
Next ❯

Citations

Nov 28, 2018·Journal of Leukocyte Biology·Lauke L BoeijenAndré Boonstra

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.