Trends in the Prevalence and Incidence of Psoriasis and Psoriatic Arthritis in Ontario, Canada: A Population-Based Study

Arthritis Care & Research
Lihi EderKaren Tu

Abstract

To estimate the prevalence and incidence of psoriasis and psoriatic arthritis (PsA) over time in Ontario, Canada. We performed a population-based study of Ontario health administrative data, using validated case definitions for psoriasis and PsA. We computed the crude and age- and sex-standardized cumulative prevalence and incidence of psoriasis from 2000 to 2015. Among the 10,774,802 individuals ages ≥20 years residing in Ontario in 2015, we identified 273,238 patients with psoriasis and 18,655 patients with PsA, equating to cumulative prevalence estimates of 2.54% and 0.17%, respectively. Correcting the prevalence estimates for imperfect sensitivity and specificity resulted in similar estimates. The male:female ratio was approximately 1.0 for both conditions. For psoriasis, the age- and sex-standardized cumulative prevalence increased from 1.74% in 2000 to 2.32% in 2015. For PsA, the age- and sex-standardized cumulative prevalence increased from 0.09% in 2008 to 0.15% in 2015. Between 2008 and 2015, annual incidence rates for psoriasis decreased, whereas those for PsA remained relatively stable. The prevalence and incidence of psoriasis and PsA in Ontario are similar to those observed in Europe and the US. The steady increase...Continue Reading

References

Jul 14, 2001·Journal of the European Academy of Dermatology and Venereology : JEADV·C FerrándizA Smandía
Oct 4, 2005·Journal of the American Academy of Dermatology·Joel M GelfandTara Rolstad
Feb 10, 2006·The Journal of Dermatological Treatment·Daniel J PearceSteven R Feldman
Oct 7, 2008·Journal of the American Academy of Dermatology·Murat IcenHilal Maradit Kremers
Jan 30, 2009·Arthritis and Rheumatism·Floranne C WilsonHilal Maradit Kremers
Jul 21, 2010·Journal of Cutaneous Medicine and Surgery·Kim PappNorman Wasel
Nov 16, 2010·The British Journal of Dermatology·N M SeminaraJ M Gelfand
Sep 28, 2012·The Journal of Investigative Dermatology·Rosa ParisiUNKNOWN Identification and Management of Psoriasis and Associated ComorbidiTy (IMPACT) project team
Feb 5, 2013·The British Journal of Dermatology·K DanielsenA-S Furberg
May 3, 2013·Pharmacoepidemiology and Drug Safety·Maryam M AsgariLisa J Herrinton
Nov 19, 2013·Journal of the American Academy of Dermatology·Iben Marie MillerGregor B E Jemec
Apr 22, 2014·American Journal of Preventive Medicine·Charles G HelmickChristopher L Bartlett
May 31, 2015·Lancet·Wolf-Henning Boehncke, Michael P Schön
Dec 30, 2015·Arthritis Care & Research·Carmen StolwijkAstrid van Tubergen
Aug 31, 2016·Journal of the European Academy of Dermatology and Venereology : JEADV·I M MichalekS M John
Sep 1, 2016·The British Journal of Dermatology·D A SpringateD M Ashcroft
Mar 9, 2017·The New England Journal of Medicine·Christopher T RitchlinDafna D Gladman
May 10, 2017·Annals of the Rheumatic Diseases·Alexander EgebergLotus Mallbris
Jan 14, 2018·Arthritis Research & Therapy·Lihi EderDevy Zisman
Jan 18, 2019·BMJ : British Medical Journal·Rachel Chapman, John Middleton

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Citations

Jan 30, 2020·Journal of Cutaneous Medicine and Surgery·Alanna C BridgmanAaron M Drucker
Apr 21, 2020·Journal of Managed Care & Specialty Pharmacy·George BungeyJohn Woolcott
May 3, 2020·The British Journal of Dermatology·I Y K IskandarUNKNOWN Global Psoriasis Atlas
Jun 27, 2020·Journal of Cutaneous Medicine and Surgery·Weiguang XueKim Papp
May 30, 2020·BMJ : British Medical Journal·Rosa ParisiUNKNOWN Global Psoriasis Atlas
Oct 29, 2020·Rheumatology International·Małgorzata TłustochowiczBartłomiej Kisiel
Oct 6, 2020·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Tsen-Fang TsaiUNKNOWN Taiwan Rheumatology Association (TRA) and the Taiwanese Association for Psoriasis and Skin Immunology (TAPSI)
Nov 3, 2020·Rheumatology Advances in Practice·Jürgen RechMaximilian Reinhardt
Dec 1, 2020·Journal of the American Academy of Dermatology·Joshua BurshteinAmit Garg
Oct 24, 2020·Journal of the American Academy of Dermatology·Keith ColacoLihi Eder
Apr 5, 2021·Lancet·Christopher E M GriffithsJonathan N W N Barker
Apr 23, 2021·Dermatology and Therapy·Kim A PappRon B Vender
May 22, 2021·Best Practice & Research. Clinical Rheumatology·Paras KarmacharyaAlexis Ogdie
Apr 30, 2021·Clinical and Experimental Dermatology·C LecarosC De la Cruz
Aug 12, 2021·International Journal of Epidemiology·Amira M AkerHilary K Brown
Mar 30, 2021·Arthritis & Rheumatology·Paras KarmacharyaKerry Wright

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