Trends in the Surgical Management of Known or Suspected Differentiated Thyroid Cancer at a Single Institution, 2010-2018.

Thyroid : Official Journal of the American Thyroid Association
Catherine Y ZhuMichael W Yeh

Abstract

Background: The surgical management of nodular thyroid disease has been influenced by the advent of molecular diagnostics and recent guidelines recommending a more conservative approach to low-risk thyroid tumors. The purpose of this study was to assess practice changes arising from the early adoption of current literature within a single high-volume center. Methods: A retrospective cohort study of all patients evaluated or surgically treated for known or suspected thyroid cancer at a single institution was performed (2010-2018). We analyzed the yield of diagnostic thyroidectomy for indeterminate (Bethesda III and IV) nodules, the choice of initial operation for likely malignant (Bethesda V and VI) nodules, and the rate of completion thyroidectomy. The Cochran-Armitage test was used to assess the significance of any observed trends. Results: Of 2497 patients who underwent initial thyroidectomy from 2010 to 2018, 1791 patients had a tissue diagnosis of suspected or known thyroid cancer by cytopathology (Bethesda III-VI) or surgical pathology (differentiated thyroid cancer). In patients with likely malignant nodules but no clinical evidence of invasive or metastatic disease, the proportion managed with total thyroidectomy plus pr...Continue Reading

References

Feb 22, 2014·JAMA Otolaryngology-- Head & Neck Surgery·Louise Davies, H Gilbert Welch
Jan 7, 2017·Annals of Surgery·Mohamed Abdelgadir AdamJulie A Sosa
Apr 1, 2017·JAMA : the Journal of the American Medical Association·Hyeyeun LimCari M Kitahara
May 2, 2017·The Journal of Clinical Endocrinology and Metabolism·Maria PapaleontiouMegan R Haymart
Mar 29, 2018·The Journal of Clinical Endocrinology and Metabolism·Masha J LivhitsMichael W Yeh
Nov 2, 2018·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·R Mack HarrellDavid N Bimston
Feb 26, 2019·Thyroid : Official Journal of the American Thyroid Association·Trevor E AngellEllen Marqusee

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Citations

Jan 5, 2021·The Journal of Clinical Endocrinology and Metabolism·Catherine Y ZhuMasha J Livhits
Mar 2, 2021·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Max A SchummMichael W Yeh
Jul 19, 2021·Annals of Surgical Oncology·Snehal G PatelAndrew J Lee
Mar 30, 2021·The Journal of Clinical Endocrinology and Metabolism·Christine E CherellaAri J Wassner

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Methods Mentioned

BETA
surgical resection
biopsy
biopsies
dissection

Software Mentioned

Afirma Classifier Classifier

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