Trends of Antiplatelet Therapy for the Management of Moyamoya Disease in Japan: Results of a Nationwide Survey

Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association
Koichi OkiResearch Committee on Spontaneous Occlusion of Circle of Willis (Moyamoya disease)

Abstract

The efficacy and safety of antiplatelet drugs in the treatment of moyamoya disease remain unclear. This study reports results of a nationwide survey conducted in 2016 on the trends of antiplatelet therapy for moyamoya disease in Japan. Data were obtained through questionnaires related to treatment policies regarding antiplatelet drugs from each specialized stroke management department of 765 hospitals in Japan. Data were also compared between experienced facilities (defined as facilities managing more than 10 cases per year) and those less experienced (not more than 10 cases per year) to determine experts' opinion. Of the 389 departments in 375 hospitals that responded, 330 departments provided medical care for moyamoya disease. Regarding ischemic stroke, numerous departments considered the use of antiplatelet drugs "in principle" (218 departments). After surgery for ischemic moyamoya disease, the use of antiplatelet drugs for a certain period of time was the most popular opinion (74 departments). Regarding asymptomatic moyamoya disease, majority departments reported no use of APDs "in principle" (256 departments). The experienced facilities reported "no use of antiplatelet drugs" more frequently than those less experienced for...Continue Reading

Citations

Feb 26, 2019·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Shishir Kumar, Shibu V Pillai
Nov 8, 2020·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Changwen LiChengyu Xia
Mar 12, 2021·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Harishchandra Lalgudi SrinivasanJonathan Roth

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