Trends of Drug Resistance Tuberculosis from 2014 to 2018, Bale Zone, Oromia Region, Ethiopia.

Infection and Drug Resistance
Mohammed Hasen Bedaso, Falaho Sani Kalil

Abstract

Multidrug-resistant tuberculosis threatens global tuberculosis care and prevention and remains a major public health concern in many countries. In 2016, there were an estimated 490,000 cases of MDR and 110,000 more cases resistant to rifampicin (RR TB). Ethiopia is among the highest MDR TB burden countries according to the WHO. This study aims to describe the magnitude, trends, and geographical distribution of the drug-resistant TB in Bale Zone during study period. A descriptive study was conducted. We reviewed secondary data of MDR and RR TB cases from July 2014 to June 2018. Data were extracted from the Bale zone health management information system database, checked for completeness, and then analyzed for trends over time. A total of 43 cases (67.4% female) of drug-resistant TB were reviewed, with 30.2% MDR and 69.8% RR TB. The prevalence of drug-resistant tuberculosis cases declined from 0.81% to 0.62% (trend χ2=2.18; P=0.14) during study period. Among drug-resistant TB cases, RR TB increased from 52.6% to 81% (trend χ2=6.5; P=0.01). Drug-resistant TB decreased over the period studied, although the trend did not reach statistical significance. These trends may reflect the efficacy of TB control programs to reduce drug-resis...Continue Reading

References

Feb 17, 2015·Antimicrobial Resistance and Infection Control·Fantahun BiadglegneArne C Rodloff
Sep 4, 2015·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Girma MulisaGodana Jarso
Nov 10, 2016·Revista Do Instituto De Medicina Tropical De São Paulo·Valdes Roberto BollelaMaria de Lourdes Viude Oliveira
Sep 30, 2017·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Ning-Ning TaoHuai-Chen Li
Jun 1, 2018·Journal of Pathogens·Solomon Weldegebreal AsgedomHailay Gebreyesus

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