Trends of presentation and clinical outcome of treated renal angiomyolipoma.

Yonsei Medical Journal
Kyo Chul KooYoung Deuk Choi

Abstract

The purpose of this study is to set guidelines for the management of renal angiomyolipoma (AML), clinical prognosis according to tumor size, in association with tuberous sclerosis complex (TSC), multiplicity, radiographic finding, and treatment modality. Between March 1998 and October 2008, 129 out of 254 patients with AML who underwent surgical intervention or angioembolization were enrolled. Diagnosis of AML was determined by the presence of a low attenuated component on CT imaging or by pathological confirmation. Indications of treatment were intractable pain, hematuria, suspicion of malignancy, large tumor size, spontaneous rupture, and radiographically equivocal tumors in which a differential diagnosis was needed to rule out malignancy. Parameters including age, sex, tumor size, multiplicity, radiographic characteristics, association with TSC, and treatment modality were reviewed. Age at presentation was 50.6 years and mean tumor size was 3.5 cm. Presentation symptoms were flank pain, hematuria, spontaneous rupture, and fatigue. 97 (75.2%) patients were incidentally discovered. 100 (77.5%) were females. 68 (52.7%) underwent nephron-sparing surgery (NSS), 35 (27.1%) radical nephrectomy, and 26 (20.2%) angioembolization. TSC...Continue Reading

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Citations

May 12, 2012·Journal of Biomedicine & Biotechnology·Keisuke MiyakeTakashi Tamiya
Oct 4, 2011·Journal of Clinical Imaging Science·Rupa Radhakrishnan, Sadhna Verma
May 28, 2014·Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie·R Le Huu NhoY P Le Treut
Jun 4, 2013·Virchows Archiv : an International Journal of Pathology·Vikas MehtaMaria M Picken
Aug 19, 2011·Clinical and Experimental Nephrology·Suguru ShirotakeShoji Matsuzaki
Dec 5, 2012·BJU International·Andrew R Lienert, David Nicol
Aug 19, 2015·World Journal of Surgical Oncology·Yuki KobariKazunari Tanabe
Apr 29, 2015·The Journal of Urology·Timothy E MurrayMichael Lee
Jul 24, 2015·AJR. American Journal of Roentgenology·Rahmin A Rabenou, Hearns W Charles
Aug 17, 2016·La Presse médicale·Yassine Er RahaliGhizlaine Belmejdoub
Dec 9, 2016·Therapeutic Advances in Urology·John J Bissler, John C Kingswood
Dec 21, 2017·Cardiovascular and Interventional Radiology·Timothy E Murray, Michael J Lee
Nov 9, 2018·Journal of Nephrology·Angela VolpiMario Cozzolino
Feb 12, 2019·Kidney Cancer·Tim J van OostenbruggePeter F A Mulders
Oct 17, 2018·International Urology and Nephrology·Burak ArslanEnver Ozdemir

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Methods Mentioned

BETA
prophylactic surgery

Software Mentioned

Statistical Package for Social Sciences

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