PMID: 2505288Jan 1, 1989Paper

Triazolam attenuates amphetamine but not morphine conditioned place preferences

Psychopharmacology
H O PettitK Mueller

Abstract

In a series of four experiments the benzodiazepine triazolam was tested for reinforcing effects and for effects on reinforcement induced by amphetamine and morphine. Reinforcement was assessed in a conditioned place preference paradigm. Triazolam did not produce reinforcing or aversive effects when administered in doses ranging from 0.0625 to 0.5 mg/kg. Triazolam did attenuate reinforcing effects produced by 0.75 and 1.25 mg/kg amphetamine. No effect of triazolam was observed on morphine-induced reinforcement. These results indicate that the administration of triazolam can affect the brain mechanisms that mediate the reinforcing effects of amphetamine but not morphine.

References

Jun 1, 1977·Pharmacology, Biochemistry, and Behavior·D C RobertsH C Fibiger
Nov 1, 1979·Pharmacology, Biochemistry, and Behavior·W H LynessK E Moore
Jan 1, 1985·Pharmacology, Biochemistry, and Behavior·W B Mackey, D van der Kooy
Jan 1, 1981·Psychopharmacology·R R GriffithsJ D Snell
Aug 1, 1983·The Journal of Pharmacy and Pharmacology·V H SethyC L Daenzer
Apr 20, 1984·European Journal of Pharmacology·S E Lukas, R R Griffiths
Dec 16, 1982·Brain Research·C SpyrakiA G Phillips
May 1, 1980·Pharmacology, Biochemistry, and Behavior·D C RobertsH C Fibiger

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Citations

Apr 1, 1992·Pharmacology, Biochemistry, and Behavior·G Di ScalaG Sandner
Jan 1, 1995·Neuroscience and Biobehavioral Reviews·M T BardoM J Harris
Feb 11, 1999·Pharmacology, Biochemistry, and Behavior·E MeririnneT Seppälä
Jul 3, 1999·Progress in Neuro-psychopharmacology & Biological Psychiatry·E MeririnneT Seppälä
May 23, 2000·Drug Metabolism and Drug Interactions·M W Jann, L J Cohen
May 26, 2004·Pharmacology, Biochemistry, and Behavior·James E Goeders, Nick E Goeders
Nov 22, 2005·Pharmacology, Biochemistry, and Behavior·Brendan M Walker, Aaron Ettenberg
Jan 1, 1993·Neuroscience and Biobehavioral Reviews·M D Schechter, D J Calcagnetti

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