Trichloromethylthiolation of N-Heterocycles: Practical and Completely Regioselective

Chemistry : a European Journal
Johannes B ErnstFrank Glorius

Abstract

The first trichloromethylthiolation of a broad range of indoles and pyrroles is reported employing bench-stable N-trichloromethylthiosaccharin as reagent. This methodology is highly regioselective, exhibits high functional group tolerance, and provides access to two previously unknown classes of potentially bioactive compounds.

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Citations

Jun 18, 2017·Organic & Biomolecular Chemistry·Fu-Xiang WangShi-Kai Tian

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