Trichoflectin, a bioactive azaphilone from the ascomycete Trichopezizella nidulus

Journal of Natural Products
E ThinesO Sterner

Abstract

Trichoflectin (1), a new azaphilone belonging to the deflectin series, 6-deoxy-7-0-demethyl-3,4-anhydrofusarubin (2), and 6-deoxy-3,4-anhydrofusarubin (3) were isolated from submerged cultures of the ascomycete Trichopezizella nidulus. All compounds showed antimicrobial activity and inhibited dihydroxynaphthalene melanin biosynthesis in fungi. The structure of trichoflectin (1) was elucidated by spectroscopic methods.

References

Jun 1, 1989·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·H AnkeO Sterner
Feb 1, 1986·The Journal of Antibiotics·I KurobaneA Fukuda

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Citations

Apr 16, 2013·Chemical Reviews·Jin-Ming GaoJian-Chun Qin
Nov 21, 2007·Mycological Research·Giovanni PacioniFrancesco Paolocci
Aug 25, 2016·Journal of Natural Products·Yan-Hui ZhouHong-Xiang Lou
Jul 22, 2017·Organic Letters·Mehdi MakrerougrasXavier Franck
Aug 1, 2020·Archives of Microbiology·Urszula Perlińska-LenartJoanna S Kruszewska
Feb 19, 2021·Accounts of Chemical Research·Suman ChakrabartyAlison R H Narayan
Nov 7, 2019·Journal of the American Chemical Society·Joshua B PyserAlison R H Narayan
May 18, 2000·The Journal of Organic Chemistry·B Kesteleyn, N De Kimpe
Dec 19, 2021·Applied Microbiology and Biotechnology·Lujie Liu, Zhilong Wang

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