Trichosporon asahii as a prospective pathogen in solid organ transplant recipients

Mycoses
I NetsvyetayevaM Luczak

Abstract

Trichosporon spp. is not an important factor of mycotic infections in immunocompetent patients. It may be a cause of invasive mycoses with a high mortality rate in patients undergoing solid organ transplantation. We have analysed the antifungal agents' susceptibility of Trichosporon asahii and its frequency of occurrence as a prospective etiological agent of infections in liver, kidney and simultaneous pancreas-kidney transplant recipients. Clinical specimens (urine, blood, peritoneal fluid and swabs) were obtained from patients hospitalised in the Institute of Transplantation Medicine, Department of General and Transplantation Surgery, Medical University of Warsaw in 2005 and 2006. Microbiological tests were performed in Mycological Laboratory, Department of Microbiology, Medical University of Warsaw. A total of 475 strains of yeast-like fungi were isolated from clinical specimens taken from 263 liver, kidney and simultaneous pancreas-kidney transplant recipients and from 26 organ donors. Trichosporon asahii was found in 26 clinical samples taken from 18 patients and one organ donor. Positive cultures were obtained from 22 urine samples, one stoma fluid, one wound swab, one tracheal aspirate and one ejaculate. Isolates of Tric...Continue Reading

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Citations

Nov 12, 2010·Medical Mycology·Emmanuel Roilides, Maria Simitsopoulou
Oct 28, 2011·Expert Review of Anti-infective Therapy·Morena CairaLivio Pagano
May 30, 2013·Infectious Disease Clinics of North America·Shmuel Shoham
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Jun 23, 2015·Transplant Infectious Disease : an Official Journal of the Transplantation Society·V ChaitanyaV Siva Kumar
Mar 1, 2012·Revista Do Instituto De Medicina Tropical De São Paulo·Everardo Albuquerque MenezesAntônio Alexandre de Vasconcelos Júnior
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Sep 13, 2019·Fungal Genetics and Biology : FG & B·Ana Carolina Barbosa PadovanArnaldo Lopes Colombo

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