Trichothecenes: reference materials and method validation

Toxicology Letters
R JosephsE Anklam

Abstract

The frequent contamination of food and feed with trichothecene mycotoxins, the high consumption of these products, and the potential risk associated herewith, has led to an increasing public awareness and therefore to the establishment of measures to control trichothecene contamination. The analytical difficulty and the economic importance of controlling trichothecenes in food and feed support the need for certified reference materials (CRMs) and validated methods. They form invaluable tools to ensure comparability and traceability in analytical measurements and are very useful for the implementation of written standards, legislation/regulations and laboratory accreditation. The present paper provides an overview of previous work, current strategies and prospectives for the production of CRMs and validation of analytical methods in the field of trichothecene analysis. Additional information is given on methodological demands, normative frameworks and commonly accepted procedures.

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Citations

Feb 21, 2014·Archives of Environmental Contamination and Toxicology·Gauri A ChandratreA K Sharma
Feb 21, 2008·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·Rudolf KrskaColin Crews
Apr 1, 2009·International Journal of Molecular Sciences·Irena Kralj Cigić, Helena Prosen
Jun 1, 2011·Food Additives & Contaminants. Part B, Surveillance·Hyun Ee OkHyang Sook Chun
Mar 27, 2010·Applied Microbiology and Biotechnology·Robert KöppenIrene Nehls
Aug 26, 2014·International Journal of Food Microbiology·Matias Pasquali, Quirico Migheli
Jul 3, 2009·International Journal of Dermatology·Aline Vansan MarangonLuzmarina Hernandes
Jul 30, 2008·Journal of Animal Physiology and Animal Nutrition·B WichertM Wanner
Apr 4, 2015·Critical Reviews in Food Science and Nutrition·Lijuan XieYibin Ying
Apr 30, 2019·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·Sang Yoo LeeHyang Sook Chun
May 6, 2009·The Journal of Immunology : Official Journal of the American Association of Immunologists·Päivi KankkunenSampsa Matikainen
Sep 2, 2020·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·Carlos GonçalvesJoerg Stroka
Feb 6, 2020·Planta medica·Ying GaoHanli Ruan
Oct 29, 2020·Human & Experimental Toxicology·Shafiqur RahmanShahid Prawez
Jul 13, 2021·Toxicon : Official Journal of the International Society on Toxinology·Judit M PomothyErzsébet Pászti-Gere

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