Tricuspid valve regurgitation attributable to endomyocardial biopsies and rejection in heart transplantation
In the present report the prevalence, severity, and risk factors of tricuspid valve regurgitation (TR) in 251 heart transplant recipients have been analyzed retrospectively. Tricuspid valve function was studied by color-flow Doppler echocardiogram and annual heart catheterization. The presence or severity of TR was graded on a scale from 0 (no TR) to 4 (severe). Additional postoperative data included rate of rejection, number of endomyocardial biopsies, incidence of transplant vasculopathy, and preoperative and postoperative hemodynamics. The incidence of grade 3 TR increases from 5% at 1 year to 50% at 4 years after transplantation. Multivariate analysis showed rate of rejection and donor heart weight to be significant risk factors. The ischemic intervals as well as the preoperative and postoperative pulmonary hemodynamics did not affect the severity or prevalence of TR. These results indicate that various factors appear to have an impact on the development of TR and that the prevalence might be lowered by a reduction of the number of biopsies performed and when possible, oversizing of donor hearts.
An alternative technique for orthotopic cardiac transplantation, with preservation of the normal anatomy of the right atrium
Right and left ventricular function after cardiac transplantation. Changes during and after rejection
Intraoperative echocardiography to detect and prevent tricuspid valve regurgitation after heart transplantation
Quantification of tricuspid regurgitation by Doppler color flow mapping after cardiac transplantation
Ruptured chordae tendineae of the tricuspid valve as a complication of endomyocardial biopsy in heart transplant patients
Left ventricular function, tricuspid incompetence, and incidence of coronary artery disease late after orthotopic heart transplantation
Accelerated coronary vascular disease in the heart transplant patient: coronary arteriographic findings
Tricuspid flail leaflets after orthotopic heart transplant: a new complication of endomyocardial biopsy
The impact of early postoperative cyclosporine serum levels on the incidence of cardiac allograft rejection
Tricuspid valve chordal tissue in endomyocardial biopsy specimens of patients with significant tricuspid regurgitation
Etiological factors influencing the development of atrioventricular valve incompetence after heart transplantation
Donor tricuspid annuloplasty during orthotopic heart transplantation: long-term results of a prospective controlled study
Tricuspid annuloplasty significantly reduces early tricuspid regurgitation after biatrial heart transplantation
Geometric disproportion of cardiac structure and graft ischemia affect tricuspid valve regurgitation early after neonatal heart transplantation
Variation in the use of surveillance endomyocardial biopsy among pediatric heart transplant centers over time
Tricuspid valve injury after heart transplantation due to endomyocardial biopsy: an analysis of 3550 biopsies
The yield of surveillance endomyocardial biopsies as a screen for cellular rejection in pediatric heart transplant patients
Endomyocardial biopsy-related tricuspid regurgitation after orthotopic heart transplantation: single-center experience
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