Trifecta outcomes after robot-assisted laparoscopic radical prostatectomy

BJU International
Giacomo NovaraWalter Artibani

Abstract

To evaluate the trifecta outcome and its preoperative predictors in a series of consecutive patients who underwent robot-assisted laparoscopic radical prostatectomy (RALP). We collected prospectively the clinical data of 242 consecutive patients with a minimum 12-month follow-up undergoing RALP for clinically localized prostate cancer. International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form (ICIQ-UI SF) and the International Index of Erectile Function (IIEF)-6 were used to evaluate the functional outcomes. Patients receiving adjuvant therapies or with a PSA at follow-up > 0.2 ng/mL were censored for the biochemical recurrence-free analysis. Logistic regression was used to perform univariable and multivariable analyses. Twelve months after surgery, 216 patients (89%) were continent and 145 (60%) were potent. At a median follow-up of 14 mo, 11 patients (4.5%) had either adjuvant radiation therapies within 3 months of surgery, when PSA was still undetectable (n= 6, 2.5%), or salvage radiation or hormone plus radiation therapy for PSA relapse (n= 5, 2%). A trifecta outcome was achieved by 137 patients (57%). On univariable regression analysis, patients' age at surgery (P < 0.001), body-mass index (P...Continue Reading

Associated Clinical Trials

References

Nov 1, 1994·Journal of Clinical Epidemiology·M CharlsonJ Gold
Feb 12, 1997·JAMA : the Journal of the American Medical Association·J E JohanssonH O Adami
Dec 4, 2003·European Urology·Laurent SalomonClément-Claude Abbou
Jul 1, 2004·Neurourology and Urodynamics·Kerry AveryPaul Abrams
May 5, 2005·JAMA : the Journal of the American Medical Association·Peter C AlbertsenJudith Fine
Dec 2, 2006·European Urology·Jens-Uwe StolzenburgEvangelos N Liatsikos
Oct 9, 2007·European Urology·Axel HeidenreichUNKNOWN European Association of Urology
Apr 22, 2008·The Journal of Urology·James A EasthamMichael W Kattan
May 16, 2008·Urologia Internationalis·Walter ArtibaniVincenzo Ficarra
Jun 19, 2008·JAMA : the Journal of the American Medical Association·Bruce J TrockPatrick C Walsh
Aug 13, 2008·Journal of the National Cancer Institute·Anna Bill-AxelsonUNKNOWN Scandinavian Prostate Cancer Group Study Number 4
Jul 14, 2009·Urology·Sergey A ShikanovArieh L Shalhav
Sep 17, 2009·JAMA : the Journal of the American Medical Association·Grace L Lu-YaoSiu-Long Yao
Oct 20, 2009·The Journal of Urology·Vincenzo FicarraWalter Artibani

❮ Previous
Next ❯

Citations

Feb 3, 2011·Langenbeck's Archives of Surgery·Gencay HatibogluMarkus Hohenfellner
Apr 9, 2013·Current Urology Reports·Kuo-How HuangJim C Hu
Dec 13, 2012·Journal of Endourology·Khurshid R GhaniMani Menon
Nov 19, 2013·Journal of Comparative Effectiveness Research·Kuo-How HuangJim C Hu
Aug 3, 2014·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·R SchiavinaE Brunocilla
Oct 23, 2012·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·Y C OuV R Patel
Nov 2, 2015·Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie·L SalomonM Soulié
Jun 14, 2013·BJU International·Leonardo D BorregalesKetan K Badani
Nov 5, 2015·Journal of Robotic Surgery·Low Wei Xiang AlvinLee Lui Shiong
Dec 11, 2020·Indian Journal of Surgical Oncology·Kulthe Ramesh Seetharam BhatR Anil Kumar

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.