Trigeminovascular stimulation in conscious rats

Neuroreport
R H KemperG J Ter Horst

Abstract

Intracisternal infusion of capsaicin was used to induce intracranial trigeminovascular stimulation in conscious rats. Both behaviour and trigeminal nucleus caudalis c-fos expression were examined. Exploratory behaviour was dose-dependently reduced and different types of behaviours were induced with various doses of capsaicin. Head grooming and scratching show that intracranial activation of trigeminal afferents can be referred as extracranial trigeminal stimulation. Analysis of behaviour exhibited during trigeminovascular stimulation may provide a powerful tool to study effects of central acting anti-migraine drugs.

Citations

Aug 29, 2000·Cephalalgia : an International Journal of Headache·R H KemperG J Ter Horst
Jul 27, 2001·Cephalalgia : an International Journal of Headache·R H KemperG J Ter Horst
Feb 15, 2002·Cephalalgia : an International Journal of Headache·G J Ter HorstR H Kemper
Jan 28, 2009·The Journal of Headache and Pain·Fabiano C TanuriDébora Amado
Jul 20, 2007·Headache·Michael L Oshinsky, Sumittra Gomonchareonsiri
Nov 16, 2011·Headache·Esther Martínez-GarcíaJosé A Terrón
Aug 27, 2014·PloS One·Shuang ZhangMin Jiang
Oct 19, 1999·Cephalalgia : an International Journal of Headache·G A LambertA S Zagami

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