Triglyceride predicts cardiovascular mortality and its relationship with glycaemia and obesity in Chinese type 2 diabetic patients

Diabetes/metabolism Research and Reviews
W B ChanJ C N Chan

Abstract

To examine the lipid profile in Chinese type 2 diabetic patients and their relationship with anthropometric parameters, glycaemic control and cardiovascular mortality. A consecutive cohort of 562 newly referred patients with type 2 diabetes to a hospital-based diabetes centre were examined in 1996. Subjects treated with lipid lowering drugs at the time of referral were excluded. A total of 517 subjects were followed up over a mean (+/-SD) period of 4.6 +/- 0.9 years. Glycated haemoglobin (HbA1c), fasting insulin and lipid profile and anthropometric parameters were documented at the time of recruitment. Cardiovascular mortality, mainly due to coronary heart disease and stroke, was ascertained using death registry and review of hospital case notes in 2001. Of the 517 subjects (mean age of 54.0 +/- 14.0 years), 42.6% were men. In this cohort, 63.3% of subjects were either overweight (BMI > or = 23 kg/m2) or obese (BMI > or = 25 kg/m2) using Asian criteria. The mean (+/-SD) total cholesterol (TC), LDL-Cholesterol (LDL-C), HDL-Cholesterol (HDL-C) and geometric mean (x// antilog SD) of triglycerides (TG) were 5.6 +/- 1.3 mmol/L, 3.6 +/- 1.1 mmol/L, 1.3 +/- 0.3 mmol/L and 1.46x//1.90 mmol/L respectively. TC and LDL-C correlated positi...Continue Reading

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Citations

Jan 10, 2014·Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine·Hirohito SoneNobuhiro Yamada
Oct 25, 2007·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·R RossJ-P Després
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Apr 24, 2018·Annals of Vascular Diseases·Kazuya Fujihara, Hirohito Sone
Aug 8, 2021·Diabetes Research and Clinical Practice·Cheng-Chieh LinTsai-Chung Li
Sep 22, 2021·Experimental Gerontology·Israel S RibeiroRobson A A Silva

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