Trimester specific reference ranges for serum TSH and Free T4 among United Arab Emirates pregnant women

Practical Laboratory Medicine
Aly Bernard KhalilLaila O Abdel Wareth

Abstract

The American Thyroid Association (ATA) recommended the establishment of population specific reference ranges for thyroid hormones during pregnancy. Initial studies conducted in the United Arab Emirates (UAE) in 2003 and 2004 on pregnant women published a considerably higher upper limit for thyroid stimulating hormone (TSH) than that proposed by ATA. The UAE was classified as a country with mild iodine deficiency at the time of this initial study. After the implementation of aggressive strategies to address iodine deficiency over the last decade, the UAE was recently declared as iodine sufficient. The current study re-evaluates the reference intervals for thyroid hormones for pregnant women in the UAE after the declaration of iodine sufficiency status. TSH and free thyroxin (FT4) from 414 UAE national pregnant females were analyzed to determine trimester specific reference ranges. The upper limits of the TSH reference ranges were found to be significantly lower than previously reported, but still higher than those recommended by ATA in 2011.FT4 reference ranges were found to be slightly lower than previously reported. TSH trimester specific reference ranges in UAE national pregnant women are higher than those recommended by ATA ...Continue Reading

Citations

Jul 28, 2020·Biological Trace Element Research·Bassem Refaat, Firas Azzeh
Jul 31, 2019·Biological Trace Element Research·Sima NazarpourFereidoun Azizi
Apr 15, 2021·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·Chaochao MaJuntao Liu
May 18, 2021·International Journal of Clinical Practice·Ömercan TopaloğluAhsen Banu Tiryaki Aylıkcı

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