Triphasic polymeric corneal coating gel versus a balanced salt solution irrigation during cataract surgery: A postoperative anterior segment optical coherence tomography analysis and confocal microscopy evaluation

Journal of Cataract and Refractive Surgery
Rita MencucciStanislao Rizzo

Abstract

To investigate the safety and efficacy of the intraoperative use of a triphasic polymeric gel as corneal coating during cataract surgery and its effect on postoperative ocular comfort. Eye Clinic, University of Florence, Italy. Longitudinal observational retrospective study. Data on patients who received an application of a polysaccharide blend of hydroxypropyl methylcellulose, xanthan gum, and carrageenan (EyeDRO) on the corneal surface and data on patients who received a balanced salt solution during phacoemulsification surgery were analyzed. The central corneal thickness (CCT) and epithelial thickness were examined using anterior segment optical coherence tomography, and the corneal basal epithelial cell (BEC) and Langerhans cell densities by in vivo confocal microscopy. The ocular surface disease index (OSDI) score, tear breakup time (TBUT), and Schirmer test I values were evaluated. The study comprised data on 28 patients in the coating gel group and 26 patients in the balanced salt solution group. In the coating gel group, the CCT and epithelial thickness values returned to the baseline value within 5 and 15 postoperative days, respectively; the BEC and Langerhans cell densities returned to baseline levels within 15 and 3...Continue Reading

References

Jan 10, 2001·Current Opinion in Ophthalmology·J N Simone, M M Whitacre
May 4, 2011·Japanese Journal of Ophthalmology·Jae Ryun KimHyun Seung Kim
Nov 23, 2013·PloS One·Ngamjit KasetsuwanSupharat Jariyakosol
May 17, 2014·Current Eye Research·Carla AmicoAnna Rita Blanco
Oct 4, 2016·PloS One·Yuli ParkHyun Seung Kim
Jul 25, 2017·The Ocular Surface·José Alvaro P GomesJames S Wolffsohn

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