Triploidy and chromosomes

American Journal of Obstetrics and Gynecology
I A Uchida, V C Freeman

Abstract

In a total sample of 105 triploid spontaneous abortions and live-born and stillborn infants, the parental origin could be determined in 77%. Dispermy was the most common cause of this abnormality. Among the digynic triploids 69% resulted from retention of the second polar body. Parental ages did not differ from those of the general population except for 10 aneuploid triploids with significantly elevated parental ages. In five sibships, simple aneuploidy in another pregnancy was observed, four of them being potentially viable. Two sisters had triploid conceptions. There were four twin pregnancies, a frequency of one in 26. Only two triploids had an XYY sex chromosome complement, one of which was mosaic with loss of an autosome and the other was a chimera. A frequency of almost 50% of mothers exposed to preconception abdominal radiation is suggestive of an association between radiation and triploidy and requires further investigation.

References

Feb 29, 1976·Human Genetics·M R CreasyE D Alberman
Apr 21, 1972·Science·I A Uchida, C C Lin
Jun 1, 1971·Journal of Medical Genetics·D H Carr
Jan 1, 1982·Human Genetics·D C WallaceA E Szulman
Oct 1, 1980·Annals of Human Genetics·T HassoldP A Jacobs

❮ Previous
Next ❯

Citations

Apr 1, 1991·Journal of Electron Microscopy Technique·J Van Blerkom, G Henry
Apr 1, 1990·Molecular Reproduction and Development·M H KaufmanS Speirs
Mar 1, 1993·Molecular Reproduction and Development·C C Henery, M H Kaufman
Dec 1, 1989·Prenatal Diagnosis·S KaffeL Y Hsu
Sep 1, 1993·Prenatal Diagnosis·I KennerknechtW Vogel
Mar 1, 1989·Human Genetics·M H PietersP P Menheere
Dec 1, 1988·Journal of in Vitro Fertilization and Embryo Transfer : IVF·J Tesarík
Oct 1, 1992·Journal of Assisted Reproduction and Genetics·J SantalóA M Estop
Jul 15, 1996·Theriogenology·D LechniakM Sosnowski
Nov 15, 2000·Clinical Genetics·D E McFadden, S Langlois
May 1, 1990·Equine Veterinary Journal·M M Power, D P Leadon
Dec 1, 1991·Journal of Medical Genetics·P MerlobM Shohat
Sep 20, 2008·Molecular Cytogenetics·Maj A HulténErik Iwarsson
Nov 15, 2015·American Journal of Medical Genetics. Part a·Jennifer E PoseyAmy M Breman
May 3, 2006·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Ralitsa S ZhivkovaIlya T Vatev
Mar 25, 2014·American Journal of Obstetrics and Gynecology·Mette W JoergensenLone Sunde
Nov 27, 2009·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Qing HuanZi-Jiang Chen
Nov 13, 2015·PloS One·Nanna Brink ScholzLone Sunde
Nov 28, 2000·Annual Review of Genetics·S P Otto, J Whitton
Sep 1, 1990·Teratology·H SchwaiboldN Böhm
Nov 7, 2014·Journal of Pediatric Gastroenterology and Nutrition·Farida K LalaniMirza B Beg
Jul 22, 2005·Prenatal Diagnosis·Thomas P Slavin, Boris G Kousseff
Dec 10, 1999·American Journal of Medical Genetics·T HasegawaN Matsuo
Sep 25, 1995·American Journal of Medical Genetics·E DietzschT J de Ravel
Jun 1, 1989·Prenatal Diagnosis·J M GrahamH C Crow
May 22, 1995·American Journal of Medical Genetics·P MinyJ Horst
Jun 5, 2003·American Journal of Medical Genetics. Part a·Mathias B Forrester, Ruth D Merz
Oct 1, 1994·American Journal of Medical Genetics·G CarakushanskyS Pellegrini
Jan 1, 1989·Molecular Reproduction and Development·P DionneR Sullivan
Aug 1, 1988·American Journal of Medical Genetics·G N WilsonP Kaplan
Jan 1, 1988·Annals of the New York Academy of Sciences·E C Wood
Jun 1, 1986·British Journal of Obstetrics and Gynaecology·F ParazziniS Pampallona
Jul 1, 1993·Journal of Medical Genetics·U MüllerK G Kupke
Feb 1, 1992·Clinical Genetics·P D Maaswinkel-MooijG Beverstock
Nov 18, 2010·Expert Review of Molecular Diagnostics·Pei Hui

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.