Tripolymeric Corneal Coating Gel Versus Balanced Salt Solution Irrigation During Cataract Surgery: A Retrospective Analysis

Cornea
Pietro GiardiniJana DʼAmato Tóthová

Abstract

To compare the protective properties and ease of manipulation during cataract surgery of corneal coating with a gel (eyeDRO; AL.CHI.MI.A. S.R.L, Italy) and corneal irrigation with balanced salt solution (BSS). We analyzed the data of 51 patients receiving either eyeDRO or BSS during routine cataract surgery performed within a 20-day period in 2016. The selected parameters were intraoperative clarity and ease of manipulation; postoperative epithelial integrity; and patient discomfort. Compared with BSS irrigation, eyeDRO coating significantly increased intraoperative clarity and ease of manipulation (P < 0.01). Single application was required in eyeDRO-treated eyes, whereas BSS was applied 5.3 ± 0.4 times on average (P < 0.01). Two hours postoperatively, a normal epithelium was observed in 90.0% and 60.0% of eyeDRO-coated and BSS-irrigated eyes, respectively; punctate epithelial damage was observed in 9.7% and 40.0% (P < 0.05) of eyeDRO-coated and BSS-irrigated eyes, respectively; eye irritation and foreign body sensation were experienced by 13.0% and 37.0% of eyeDRO-treated patients and by 65.0% and 100% of BSS-treated patients, respectively (P < 0.01). Twenty-four hours postoperatively, 80.0% of BSS-treated patients versus 19....Continue Reading

References

Nov 22, 1997·Journal of Cataract and Refractive Surgery·S A Arshinoff, E Khoury
Aug 6, 2002·Journal of Cataract and Refractive Surgery·Thandalam S Kalyanasundaram, Mahmood Hasan
Mar 7, 2006·Clinica Chimica Acta; International Journal of Clinical Chemistry·Yoshiki OhashiKazuo Tsubota
Mar 15, 2008·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Santosh KhanalSubhanjan Mukerji
Jun 17, 2015·European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V·Anxo Fernández-FerreiroFrancisco Javier Otero-Espinar
Jul 1, 2015·BMC Ophthalmology·Servet CetinkayaHalil Ibrahim Yener

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Citations

Jun 25, 2020·International Ophthalmology Clinics·Tamer M HadiMitul C Mehta

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