Triptans for acute cluster headache

The Cochrane Database of Systematic Reviews
Simon LawR Andrew Moore

Abstract

This is an updated version of the original Cochrane review published in Issue 4, 2010 (Law 2010). Cluster headache is an uncommon,severely painful, and disabling condition, with rapid onset. Validated treatment options are limited; first-line therapy includes inhaled oxygen. Other therapies such as intranasal lignocaine and ergotamine are not as commonly used and are less well studied. Triptans are successfully used to treat migraine attacks and they may also be useful for cluster headache. To assess the efficacy and tolerability of the triptan class of drugs compared to placebo and other active interventions in the acute treatment of episodic and chronic cluster headache in adult patients. We searched the Cochrane Central Register of Controlled Trials (CENTRAL),MEDLINE, EMBASE, ClinicalTrials.gov, and reference lists for studies from inception to 22 January 2010 for the original review, and from 2009 to 4 April 2013 for this update. Randomised, double-blind, placebo-controlled studies of triptans for acute treatment of cluster headache episodes. Two review authors independently assessed study quality and extracted data. Numbers of participants with different levels of pain relief,requiring rescue medication, and experiencing a...Continue Reading

References

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Citations

Mar 16, 2019·Brain Sciences·Gonzalo Navarro-FernándezAlfonso Gil-Martínez
Jul 10, 2019·Current Pain and Headache Reports·Alan David KayeRichard D Urman
Jul 1, 2018·Journal of Molecular Neuroscience : MN·Martha-Spyridoula KatsarouNikolaos Drakoulis
Dec 29, 2015·The Cochrane Database of Systematic Reviews·Michael H BennettStephanie Weibel
Jun 9, 2020·Expert Review of Clinical Pharmacology·Jasper MecklenburgUwe Reuter
May 3, 2016·Therapeutic Advances in Neurological Disorders·Dagny Holle-Lee, Charly Gaul

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