PMID: 29755835May 15, 2018Paper

Trisomy 6 as the sole stemline abnormality in a patient with acute monocytic leukemia: a case report

American Journal of Blood Research
Masahiro ManabeKi-Ryang Koh

Abstract

It is rare for trisomy 6 to occur as the sole autosomal anomaly in hematological malignancies, but this finding has been reported to be associated with a hypoplastic bone marrow. We report the case of a 75-year-old male with acute monocytic leukemia, in which trisomy 6 was detected as the sole stemline abnormality. We also summarize the 26 published cases of acute myeloid leukemia involving isolated trisomy 6.

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