Tritium in [18O]water containing [18F]fluoride for [18F]FDG synthesis

Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine
Shigeki ItoKunihide Nishizawa

Abstract

The presence of tritium in enriched [18O]water irradiated with 9.6 MeV protons used to produce [18F]fluoride by the 18O(p, n)18F reaction was inferred from the cross sections and threshold energies of the 18O(p, t)16O reaction, and the existence of tritium was confirmed experimentally. Tritium was also detected in both [18O]water recovered for recycling and waste acetonitrile solutions. The purified [18F]FDG was not contaminated with 3H. The amount of 3H discharged into the air was far less than the International Basic Safety Standard Level.

References

Oct 6, 1999·Obesity Research·D Schoeller

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Citations

Apr 24, 2013·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·M KöhlerJ Konheiser
Feb 4, 2010·Nihon Hoshasen Gijutsu Gakkai zasshi·Hiroaki NagaokaShinji Tanaka
Jan 5, 2014·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·R FitzgeraldD S Moreira
Mar 1, 2011·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·Romolo RemettiM Azzurra Filannino
Dec 30, 2008·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·Louise BowdenGeorge J Duffy
Nov 18, 2005·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·Shigeki ItoKunihide Nishizawa
Jun 5, 2014·Journal of Radiological Protection : Official Journal of the Society for Radiological Protection·C MarshallW D Evans
Apr 6, 2011·Health Physics·Yoshimune OgataHajime Nakamura
Apr 16, 2014·Reports of Practical Oncology and Radiotherapy : Journal of Greatpoland Cancer Center in Poznań and Polish Society of Radiation Oncology·Krzysztof KilianAnna Pękal
Oct 10, 2020·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Andrea ChiappinielloRoberto Tarducci

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