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tRNA gene copy number variation in humans

Gene

Dec 18, 2013

James R Iben, Richard J Maraia

Abstract

The human tRNAome consists of more than 500 interspersed tRNA genes comprising 51 anticodon families of largely unequal copy number. We examined tRNA gene copy number variation (tgCNV) in six individuals; two kindreds of two parents and a child, using high coverage whole genome sequence...read more

Mentioned in this Paper

CDKAL1 gene
Genome-Wide Association Study
Gene Dosage
Multigene Family
Specimen Type - Fibroblasts
DNA Copy Number Changes
Genome
Amino Acids, I.V. solution additive
MT-TA gene
Triplet Codon-amino Acid Adaptor Activity
1
77
Paper Details
References
  • References42
  • Citations17
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  • References42
  • Citations17
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tRNA gene copy number variation in humans

Gene

Dec 18, 2013

James R Iben, Richard J Maraia

PMID: 24342656

DOI: 10.1016/j.gene.2013.11.049

Abstract

The human tRNAome consists of more than 500 interspersed tRNA genes comprising 51 anticodon families of largely unequal copy number. We examined tRNA gene copy number variation (tgCNV) in six individuals; two kindreds of two parents and a child, using high coverage whole genome sequence...read more

Mentioned in this Paper

CDKAL1 gene
Genome-Wide Association Study
Gene Dosage
Multigene Family
Specimen Type - Fibroblasts
DNA Copy Number Changes
Genome
Amino Acids, I.V. solution additive
MT-TA gene
Triplet Codon-amino Acid Adaptor Activity
1
77

Similar Papers Found In These Feeds

Chaperones & Protein Folding

Chaperones are proteins that play an essential role in protein folding, stability, assembly, and degradation. Their depletion or dysfunction has been implicated in protein folding disorders. Here is the latest research.

Structure and Function of DNA

The double helix structure of DNA is important for its biological function. Discover the latest research on the Structure and Function of DNA here.

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Paper Details
References
  • References42
  • Citations17
12345
  • References42
  • Citations17
12
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