TRPC Channel Downstream Signaling Cascades

Advances in Experimental Medicine and Biology
Zhuohao He

Abstract

The family of TRP channel is comprised of a large group of cation-permeable channels, displaying as signaling integrators for sensing extracellular stimulus and initiating intracellular signaling cascades. This chapter offers a brief review of the signaling molecules related to TRPC channels, the first identified mammalian TRP family. Besides the signaling molecules involved in TRPC activation, I will focus on their upstream and downstream signaling cascades and the molecules involved in their intracellular trafficking.

Citations

Aug 14, 2020·Channels·Naghmeh Hassanzadeh KhayyatOleh Pochynyuk

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