Trypanosoma cruzi infection and electrocardiographic findings among active manual workers. A population-based study in central Brazil

International Journal of Epidemiology
F ZickerP G Smith

Abstract

In a cross sectional survey of the prevalence of Trypanosoma cruzi infection among urban unskilled workers in Goiânia, Brazil, blood samples from 6222 manual workers from seven institutions were examined for anti-Trypanosoma cruzi antibodies by immunofluorescence, ELISA and haemagglutination tests. ECGs were performed and a clinical history was taken from 624 seropositive and a random sample of 529 seronegative subjects. Abnormal ECGs were found in 15.1% of individuals without Trypanosoma cruzi antibodies and in 44.4% of those with antibodies (p less than 0.001). In general, cardiovascular symptoms reported were not associated with seropositivity nor with ECG alterations but dizziness and dyspnoea were more often reported among those with an abnormal tracing (p less than 0.01). The prevalence of ECG abnormalities increased with age in both groups but was higher among those seropositive in all age groups. An odds ratio of 2.0 (95% Cl 1.2-3.1) and 2.9 (95% Cl 1.5-6.3) of ECG abnormalities, for each decade of life, was estimated for seropositive and seronegative subjects, respectively. Relative risks (based on the odds ratios) for various specific ECG abnormalities, comparing seropositive to seronegative individuals, were calculat...Continue Reading

Citations

Dec 8, 2006·Heart and Vessels·Binh An P PhanWayne C Levy
Nov 1, 1990·Transactions of the Royal Society of Tropical Medicine and Hygiene·F ZickerP G Smith
Nov 13, 2015·Expert Review of Cardiovascular Therapy·Sophie MavrogeniGenovefa Kolovou
Sep 29, 2015·Journal of Cardiovascular Electrophysiology·Rhanderson CardosoRaul D Mitrani
Jun 9, 2009·International Journal for Parasitology·Julio César CarranzaBianca Zingales
Dec 28, 2007·PLoS Neglected Tropical Diseases·Michael Z LevyCaryn Bern
Mar 1, 1990·Revista Do Instituto De Medicina Tropical De São Paulo·F ZickerS Almeida e Silva
Jan 18, 2005·Revista Do Instituto De Medicina Tropical De São Paulo·Moisés GoldbaumJosé Eluf-Neto
Oct 1, 1992·Clinical Microbiology Reviews·H B TanowitzM Wittner

❮ Previous
Next ❯

Related Concepts