PMID: 9638808Jun 25, 1998Paper

Trypanotolerance, an option for sustainable livestock production in areas at risk from trypanosomosis

Revue Scientifique Et Technique
G D d'IeterenM Murray

Abstract

Trypanosomosis is one of the major constraints on animal production in areas of Africa which have the greatest potential for significant increases in domestic livestock populations and livestock productivity. While the eradication of trypanosomosis from the entire continent is an unrealistic goal, considerable effort has been invested in the control of this disease through the use of trypanocidal drugs, management of the vector and exploitation of the genetic resistance exhibited by indigenous breeds. There is little hope that a conventional, anti-infection vaccine will be produced in the near future. Drug resistance is developing faster than generally thought. The control of the tsetse fly has been attempted over many decades. The decreasing efficacy of available trypanocidal drugs and the difficulties of sustaining tsetse control increase the imperative need to enhance trypanotolerance through selective breeding, either within breeds or through cross-breeding. Trypanotolerance has been defined as the relative capacity of an animal to control the development of the parasites and to limit their pathological effects, the most prominent of which is anaemia. A major constraint on selection for trypanotolerance in cattle, for both ...Continue Reading

Citations

Apr 22, 2008·The Journal of Immunology : Official Journal of the American Association of Immunologists·Tom BosschaertsAlain Beschin
Mar 20, 2008·Mammalian Genome : Official Journal of the International Mammalian Genome Society·Eveline M Ibeagha-AwemuXin Zhao
Feb 16, 2010·Parasitology·M C Taylor, J M Kelly
Sep 26, 2014·PLoS Pathogens·Benoît StijlemansPatrick De Baetselier
Sep 16, 2016·PLoS Pathogens·Benoît StijlemansPatrick De Baetselier
Feb 26, 2010·Journal of Biomedicine & Biotechnology·Toya Nath Baral
Dec 1, 2006·Annals of the New York Academy of Sciences·David BerthierJean-Charles Maillard
Feb 22, 2017·Genome Biology·Jaemin KimHeebal Kim
Jul 5, 2017·Parasitology Research·Nthatisi Innocentia MolefeNoboru Inoue
Jun 26, 2010·Tropical Animal Health and Production·Abebayehu Tadesse, Biniam Tsegaye
Jan 6, 2009·Annals of the New York Academy of Sciences·David BerthierGerard Cuny
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Feb 10, 2009·Trends in Parasitology·Stanny GeertsDéthié Faye
Jul 8, 2010·Immunobiology·Ann VankrunkelsvenBenoît Stijlemans

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