Tryptophol and derivatives: natural occurrence and applications to the synthesis of bioactive compounds

Natural Product Reports
Alessandro Palmieri, Marino Petrini

Abstract

Covering: up to 2018 Tryptophol (indole-3-ethanol) is a metabolite produced by plants, bacteria, fungi and sponges. This review reports on the natural occurrence, bioactivity and various synthetic approaches to the preparation of tryptophol and its derivatives. Syntheses of various naturally occurring tryptophol derivatives known for their enhanced pharmacological profile are also presented.

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Citations

Jun 4, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Giann Carlos Peñaloza AtuestaJonh Jairo Méndez Arteaga
Jan 9, 2019·Frontiers in Microbiology·Manuel PorcarTrent R Northen
Apr 5, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Jyothi Dhuguru, Rachid Skouta
Aug 14, 2021·Chemical Communications : Chem Comm·Tian-Jiao HanGuang-Jian Mei

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Methods Mentioned

BETA
hydroamination
acetylation

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