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TSPO polymorphism in individuals with alcohol use disorder: Association with cholesterol levels and withdrawal severity

Addiction Biology

Nov 12, 2019

Corinde E WiersNora D. Volkow

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Abstract

The translocator protein (TSPO) transports cholesterol into mitochondria and is involved in steroidogenesis. The TSPO polymorphism rs6971 influences binding of cholesterol and other TSPO ligands including positron-emission tomography (PET) imaging radiotracers. Although it is recognized...read more

Mentioned in this Paper

Alcohol Use Disorder
Appendicitis
Carrier Proteins
Cholesterol
Ligands
High Density Lipoproteins
Low-Density Lipoproteins
Mitochondria
Plasma
Triglycerides
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TSPO polymorphism in individuals with alcohol use disorder: Association with cholesterol levels and withdrawal severity

Addiction Biology

Nov 12, 2019

Corinde E WiersNora D. Volkow

PMID: 31713961

DOI: 10.1111/adb.12838

Abstract

The translocator protein (TSPO) transports cholesterol into mitochondria and is involved in steroidogenesis. The TSPO polymorphism rs6971 influences binding of cholesterol and other TSPO ligands including positron-emission tomography (PET) imaging radiotracers. Although it is recognized...read more

Mentioned in this Paper

Alcohol Use Disorder
Appendicitis
Carrier Proteins
Cholesterol
Ligands

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Paper Details
References
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  • References41
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