PMID: 11904595Mar 21, 2002Paper

Tubal surface lidocaine mediates pre-emptive analgesia in awake laparoscopic sterilization: a prospective, randomized clinical trial

American Journal of Obstetrics and Gynecology
Susan GarwoodJohn Guillebaud

Abstract

The purpose of this study was to determine whether lidocaine that is instilled onto the Fallopian tubes reduces pain scores in awake patients who undergo laparoscopic sterilization with Filshie clips. This was a prospective, randomized, placebo-controlled, double-blinded, clinical trial study that was approved by our institutional review board. Pain scores (visual analogue scales) were lower in the lidocaine group (n = 12 patients) than in the placebo group (n = 12 patients) at clip application (6 vs 71 mm; P <.0001) and after 15 minutes after operation (15.5 vs 44.5 mm; P <.005). No significant differences occurred at 1-hour after operation or discharge, but more rescue analgesia was required in the placebo group ( P <.05), with more side effects ( P <.05). In a separate group of 20 women, serum lidocaine levels were measured (maximum level, 16.0 micromol/L). Holter monitoring of these patients revealed no significant arrhythmias. One percent lidocaine that is instilled onto the Fallopian tubes reduces pain scores in awake patients who undergo laparoscopic sterilization with Filshie clips.

References

Oct 1, 1992·Anesthesia and Analgesia·D L Bourke
Mar 1, 1987·British Journal of Obstetrics and Gynaecology·F F DobbsM G Hull
Aug 1, 1983·American Journal of Obstetrics and Gynecology·F J SpielmanR A Mueller
Apr 1, 1996·British Journal of Obstetrics and Gynaecology·A Hunter, P Fogarty
Feb 1, 1996·Acta Anaesthesiologica Scandinavica·H ErikssonK Korttila

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Citations

Nov 27, 2007·The Veterinary Journal·Luca F ZilbersteinEléonore Leterrier
Sep 27, 2002·AORN Journal·Suzanne Beyea
Dec 13, 2005·Journal of Minimally Invasive Gynecology·Barbara S LevyLaura L Emery
May 5, 2007·Current Opinion in Anaesthesiology·Daniel T Goulson
Nov 6, 2009·Gastric Cancer : Official Journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association·Shinsuke KiriyamaTakuji Gotoda
Jan 22, 2009·Obstetrics and Gynecology·I Z MacKenzieJohn Guillebaud
Oct 5, 2006·Current Opinion in Anaesthesiology·Joel Katz, Colin J L McCartney
Oct 15, 2021·Veterinary Medicine and Science·Vincenzo CicirelliGiulio G Aiudi

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