PMID: 9432075Jan 31, 1998Paper

Tube placement: a prospective, randomized double-blind study

The Laryngoscope
C S DerkayJ O'Master

Abstract

Bilateral myringotomy with tympanostomy tube placement is the second most frequently performed pediatric surgical procedure, next to circumcision. Postoperative pain relief for children undergoing this procedure has been an ongoing concern. The authors undertook a prospective, randomized, double-blind, placebo-controlled clinical study in 200 consecutive children to investigate the efficacy of oral acetaminophen, acetaminophen with codeine, ibuprofen, and placebo administered preoperatively in relieving postoperative pain in children undergoing this procedure. All children received topical analgesia consisting of antibiotic eardrops mixed with 4% lidocaine intraoperatively. There was no significant difference in postoperative pain score between the four groups (P > 0.4447). Thus it is likely that the intraoperative administration of antibiotic eardrops mixed with 4% lidocaine is all that is required to alleviate postoperative pain in children undergoing myringotomy with tympanostomy tube placement. Preoperative oral analgesics are apparently of little added benefit.

References

Sep 1, 1992·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·M F WatchaR P Terkonda
Jun 1, 1991·British Journal of Anaesthesia·J B Dahl, H Kehlet
Jan 1, 1993·European Journal of Clinical Pharmacology·U AhlströmL Wåhlander
Jan 1, 1993·International Journal of Pediatric Otorhinolaryngology·C S Derkay
Mar 1, 1996·International Journal of Pediatric Otorhinolaryngology·C D LawhornR Shirey

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Citations

Nov 3, 2006·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Sanjay M BhanankerWilliam Splinter
Jul 5, 2011·Paediatric Anaesthesia·Jacqueline Hannam, Brian J Anderson

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