PMID: 15218960Jun 29, 2004Paper

Tuberculosis-associated hemophagocytic syndrome in a hemodialysis patient with protracted fever

International Journal of Hematology
Chih-Chiang ChienWei-Kang Kwang

Abstract

Hemophagocytic syndrome (HPS) is a clinicopathological reflection of uncontrolled activation of macrophages. To our knowledge, only a few cases of tuberculosis-associated HPS in hemodialysis have been reported in the English literature. We report a case of tuberculosis-associated HPS during hemodialysis. Bone marrow aspiration showed histiocytosis with hemophagocytosis; in addition, results of acid-fast staining and polymerase chain reaction showed the presence of acid-fast bacilli. Mycobacterium tuberculosis was subsequently cultured from sputum. The patient received late treatment with antituberculosis agents combined with intravenous immunoglobulin and had a poor response. On the basis of the results in this case, we recommend early bone marrow and tuberculous examination for patients undergoing maintenance hemodialysis who have fever of unknown origin.

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Citations

Jun 14, 2012·Bulletin de la Société de pathologie exotique·R RakotoarimananaS Ralandison
Dec 15, 2005·Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology·Nada JabadoGenevieve de Saint Basile
Dec 20, 2011·Revista clínica española·R Fernández RodríguezM Bustillo Casado
Aug 7, 2009·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Yu-Hsiang ChouShan-Chwen Chang
Jun 23, 2006·The Lancet Infectious Diseases·Priscilla K BrastianosPetros C Karakousis

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