Tuberculosis control in resource-poor countries: have we reached the limits of the universal paradigm?

Tropical Medicine & International Health : TM & IH
Christian Lienhardt, Jessica Ann Ogden

Abstract

The aim of TB control is to break the cycle of transmission by treating TB cases as early and efficiently as possible. In its efforts to promote a model of worldwide TB control, WHO defined specific targets and launched the 'Directly Observed Therapy, Short-course' (DOTS) strategy as the main tool to reach them. However, the diversity of patients' attitudes towards the disease and the extreme variability of access to care, especially in resource-poor countries, are amongst the many factors of social context that profoundly affect the ability of control programmes to implement this policy effectively. There are multiple reports of TB control programmes using various types of intervention to promote adherence and enhance case-holding, but most of these interventions depend on external funding, which bring into question their long-term sustainability. In this paper, we address the problems related to operational variabilities in the implementation of the DOTS strategy in resource-poor countries and question the appropriateness of a universal paradigm for global TB control. This analysis is of particular importance as programmers consider using this model in the delivery of anti-retroviral therapies for the treatment of HIV in reso...Continue Reading

References

Mar 15, 1992·The New England Journal of Medicine·D E Snider, W L Roper
Oct 1, 1981·British Journal of Diseases of the Chest·W Fox
Jan 18, 1995·JAMA : the Journal of the American Medical Association·M C RaviglioneA Kochi
Apr 28, 1994·The New England Journal of Medicine·S E WeisB H Foresman
Feb 1, 1993·Research in Microbiology·A KochiK Styblo
Jun 1, 1993·Tubercle and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease·M DattaR Prabhakar
May 1, 1993·The American Review of Respiratory Disease·E Sumartojo
Feb 1, 1997·Social Science & Medicine·P Farmer
Jul 19, 1997·Lancet·A M ChowdhuryJ P Vaughan
May 16, 1998·BMJ : British Medical Journal·J Green, N Britten
Aug 28, 1999·Leprosy Review·J A Ogden, J D Porter
Mar 4, 2000·Transactions of the Royal Society of Tropical Medicine and Hygiene·P KamolratanakulV Payanandana
Apr 25, 2000·Lancet·J VolminkP Garner
Jul 18, 2000·Transactions of the Royal Society of Tropical Medicine and Hygiene·J Ogden
Oct 21, 2000·Lancet·J WalleyA Khan
Mar 13, 2002·Lancet·M C Raviglione, A Pio
Jul 2, 2002·Lancet·Elizabeth L CorbettRichard J Hayes
Aug 9, 2002·Tropical Medicine & International Health : TM & IH·V SinghR C Jain
Nov 19, 2002·International Journal of Epidemiology·Thomas R Frieden
Jan 16, 2003·European Journal of Pain : EJP·Heinrich FruhstorferUlf F Lindblom
Apr 30, 2003·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Keishi MiwaTakehiko Uchiyama
Jun 28, 2003·Tropical Medicine & International Health : TM & IH·A JaiswalR C Jain
Oct 11, 2003·BMJ : British Medical Journal·Dermot MaherMario Raviglione
Oct 11, 2003·BMJ : British Medical Journal·Paul Garner, Jimmy Volmink
Aug 17, 2004·Transactions of the Royal Society of Tropical Medicine and Hygiene·M HarperC Lienhardt
Oct 14, 2005·Magnetic Resonance in Medical Sciences : MRMS : an Official Journal of Japan Society of Magnetic Resonance in Medicine·Takashi TakeguchiTakanori Ohnishi

❮ Previous
Next ❯

Citations

Mar 3, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Christopher C Whalen
Jul 4, 2013·BMC Medical Ethics·Mette SagbakkenJohn D H Porter
Jul 29, 2006·American Journal of Public Health·Krista Jane Lauer, Anne-Emanuelle Birn
Mar 30, 2010·Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række·Mette SagbakkenGunnar A Bjune
Oct 24, 2007·Tropical Medicine & International Health : TM & IH·Thomas S Moulding
Feb 13, 2008·Tropical Medicine & International Health : TM & IH·Margaret E KrukChristine A Aguiar
Jun 29, 2007·Tropical Medicine & International Health : TM & IH·Jean MacqHaileyesus Getahun
Dec 29, 2005·International Journal of Cancer. Journal International Du Cancer·Aarne LaakkonenEero Pukkala
Feb 16, 2011·British Journal of Clinical Pharmacology·Justin J WilkinsUlrika S H Simonsson
May 3, 2005·Biochimica Et Biophysica Acta·Allison ZannoHebe M Guardiola-Diaz
Jul 22, 2015·Revue de pneumologie clinique·E L P BembaE Aka Danguy
Sep 17, 2014·Global Public Health·Rubina Shiotani, Monique Hennink
Jul 20, 2016·BMC Health Services Research·Vijayashree YellappaPatrick Van der Stuyft
Aug 16, 2016·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Payam NahidAndrew Vernon
Mar 17, 2016·Revista brasileira de epidemiologia = Brazilian journal of epidemiology·Natália Sperli Geraldes Marin dos Santos SasakiFrancisco Chiaravalloti-Neto
Feb 13, 2007·Revista latino-americana de enfermagem·Paula HinoClaudia Benedita dos Santos
Apr 9, 2008·Revista latino-americana de enfermagem·Roxana Isabel Cardozo GonzálesTereza Cristina Scatena Villa
Dec 25, 2007·Revista latino-americana de enfermagem·Paula HinoClaudia Benedita dos Santos
Mar 21, 2006·Lancet·Christian Lienhardt, Roxana Rustomjee
Aug 16, 2008·Qualitative Health Research·Mette SagbakkenGunnar A Bjune
Jan 18, 2018·Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia·Marcelo Fouad RabahiMarcus Barreto Conde
Dec 1, 2018·Qualitative Health Research·Bethan HatherallMuhammad Amir Khan
May 15, 2012·Nature Reviews. Microbiology·Christian LienhardtMario Raviglione
Oct 18, 2016·Global Public Health·Ietza BojorquezTimothy C Rodwell
Feb 6, 2009·Revista da Escola de Enfermagem da U S P·Roxana Isabel Cardozo GonzalesAntonio Ruffino Netto

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.