Tuberculosis in wild South American sea lions Otaria flavescens stranded in Chubut, Argentina

Diseases of Aquatic Organisms
Carla FioritoSoledad Barandiaran

Abstract

Pinniped tuberculosis, commonly caused by Mycobacterium pinnipedii, is a zoonotic disease reported in free-living and captive otariid species of the southern hemisphere. Currently, data concerning pinniped tuberculosis in South America are scarce, reinforcing the need for further studies of the disease in free-ranging pinnipeds. In this study, we investigated the presence of tuberculosis in South American sea lions Otaria flavescens (SASLs) stranded along the Chubut coastline (Argentina). Necropsies were performed in 9 SASLs, and tissue samples were collected for histopathology, bacteriology, and molecular diagnosis. Four SASLs showed enlarged tracheobronchial lymph nodes (TBLNs) with multifocal to coalescing granulomas. In these animals, a direct IS6110-PCR amplification confirmed the presence of a Mycobacterium tuberculosis complex member in TBLNs (n = 4) and lungs (n = 2), but the agent could not be further identified. In one SASL, Mycobacterium murale was isolated from lungs without lesions. This study confirms the presence of tuberculosis in SASLs from Chubut, where tourist activities promote close interaction with the animals, generating a potential risk to human health. Further research is currently focusing on addressin...Continue Reading

References

Sep 1, 1996·Revue Scientifique Et Technique·A BernardelliE Costa
Oct 12, 1999·Microbiology·M J ZumárragaM I Romano
Sep 18, 2003·International Journal of Systematic and Evolutionary Microbiology·Debby V CousinsAmelia Bernardelli
Jun 11, 2005·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Martín J ZumárragaAngel Cataldi
Jun 1, 2011·Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians·Kerstin JurczynskiPierre Moisson
Jan 1, 2013·Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians·Leigh Ann ClaytonJoseph L Mankowski
Feb 4, 2014·Journal of Wildlife Diseases·Derek B de AmorimJosé S Ferreira-Neto
Nov 9, 2016·Advances in Experimental Medicine and Biology·I PorvaznikJ Mokrý
Jun 13, 2019·Diseases of Aquatic Organisms·Aryse Martins MeloMelissa Orzechowski Xavier

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