Tuberculosis Mortality in the United States: Epidemiology and Prevention Opportunities.

Annals of the American Thoracic Society
Suzanne F BeaversTuberculosis Epidemiologic Studies Consortium

Abstract

Rationale: More information on risk factors for death from tuberculosis in the United States could help reduce the tuberculosis mortality rate, which has remained steady for more than a decade.Objective: To identify risk factors for tuberculosis-related death in adults.Methods: We performed a retrospective study of 1,304 adults with tuberculosis who died before treatment completion and 1,039 frequency-matched control subjects who completed tuberculosis treatment in 2005 to 2006 in 13 states reporting 65% of U.S. tuberculosis cases. We used in-depth record abstractions and a standard algorithm to classify deaths in persons with tuberculosis as tuberculosis-related or not. We then compared these classifications to causes of death as coded in death certificates. We used multivariable logistic regression to calculate adjusted odds ratios for predictors of tuberculosis-related death among adults compared with those who completed tuberculosis treatment.Results: Of 1,304 adult deaths, 942 (72%) were tuberculosis related, 272 (21%) were not, and 90 (7%) could not be classified. Of 847 tuberculosis-related deaths with death certificates available, 378 (45%) did not list tuberculosis as a cause of death. Adjusting for known risks, we ide...Continue Reading

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Citations

Feb 16, 2020·Journal of Racial and Ethnic Health Disparities·K M SchmitS M Marks
Jan 17, 2019·American Journal of Public Health·Julie Higashi, Pennan Barry
Aug 1, 2020·Journal of Public Health Management and Practice : JPHMP·Suzanne M MarksEdward A Graviss
May 3, 2019·American Journal of Respiratory and Critical Care Medicine·Michael S NiedermanNeil W Schluger
Jun 25, 2019·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Lisa SharlingSundari Mase
Feb 1, 2020·The Science of the Total Environment·Robert J BlountDonald G Catanzaro

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Methods Mentioned

BETA
nucleic acid amplification

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