Tuberculous peritonitis complicating long-term peritoneal dialysis. Report of 5 cases and review of the literature

American Journal of Nephrology
I K ChengM K Chan

Abstract

The characteristics of 5 patients who developed tuberculous peritonitis while receiving long-term peritoneal dialysis (PD) are presented. There were 2 males and 3 females. 3 patients were on intermittent and 2 were on continuous ambulatory peritoneal dialysis when tuberculous peritonitis was first diagnosed. None of the patients had recently received immunosuppression therapy or were diabetics. The clinical presentations were similar to other forms of peritonitis complicating PD except for a more insidious onset. As extraperitoneal involvement and peritoneal lymphocytosis were rarely present, the diagnosis was mainly dependent on the direct demonstration of Mycobacterium tuberculosis with smear (1 patient) and culture (4 patients). In 1 patient with a pleuroperitoneal communication, the diagnosis was made by pleural biopsy and a positive response to antituberculous therapy. All patients responded to treatment with a combination of three antituberculous drugs which included streptomycin, isoniazid, rifampicin and pyrazinamide. Two patients were transferred to hemodialysis. In 3 patients, peritoneal dialysis was continued. Peritoneal clearance and ultrafiltration capacity were unchanged for up to 16 months after treatment in 2 pa...Continue Reading

Citations

Sep 26, 2001·Infectious Disease Clinics of North America·F D PienB C Pien
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Jul 29, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·R Talwani, J A Horvath
Jan 11, 2013·The American Journal of Tropical Medicine and Hygiene·Elizabeth De Francesco DaherElvino José Guardão Barros
Jun 1, 1992·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·M GiladiC B Panosian
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Feb 12, 2017·Microbiology Spectrum·Urvashi Vaid, Gregory C Kane

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