Abstract
Our objective was to review the presentation and management of patients with tubular breast cancer treated at Barnes-Jewish Hospital and compare our findings with the available literature. Of 3908 cases of breast cancer treated at our institution between 1986 and 1995, the incidence of tubular breast cancer at Barnes-Jewish Hospital was 1.25%. We reviewed the breast cancer risks, initial presentation, treatment, and outcome of 39 women with 40 tubular breast cancers and compared our series with others in the literature. The mean patient age was 67 years, which is older than most other series. Twenty-nine of the 39 cancers (74%) were detected by screening mammography; the remainder presented with a palpable breast mass. The mean tumor size was 8 mm (range, 1-60 mm). Twenty-three of 25 tumors were ER+ (92%) and none had axillary nodal involvement. Bilateral breast cancer developed in 3 patients (8%). An additional 500 cases of tubular breast cancer have been described in the literature. When the component of the invasive tumor is > 75% tubular carcinoma, most patients present with early-stage disease that is ER+ in 47 of 56 tumors (84%). The natural history is indolent and metastases are rare. Bilateral breast cancer developed in...Continue Reading
References
Nov 1, 1978·Radiology·S A FeigR Nerlinger
Mar 1, 1985·Histopathology·P H CarstensH Lyon
Mar 1, 1970·Cancer·H B Taylor, H J Norris
Dec 1, 1993·AJR. American Journal of Roentgenology·B C ElsonD D Adler
Feb 1, 1993·AJR. American Journal of Roentgenology·A J LeibmanB Kruse
Mar 1, 1996·Annals of Surgery·D J WinchesterS E Singletary
Citations
Jul 16, 2009·Annals of Oncology : Official Journal of the European Society for Medical Oncology·R YerushalmiK A Gelmon
Mar 15, 2013·Genes & Cancer·Brittni A SmithBryan E Welm
Aug 1, 2013·American Journal of Epidemiology·Sarah J NyanteLouise A Brinton
Sep 1, 2012·Surgical Pathology Clinics·Timothy M D'Alfonso, Sandra J Shin
May 1, 2012·International Journal of Radiation Oncology, Biology, Physics·Baoqing LiSteven L Chen
Apr 24, 2009·International Journal of Radiation Oncology, Biology, Physics·Gene-Fu F LiuMeena S Moran
Feb 22, 2012·Journal of Medical Imaging and Radiation Oncology·Carmen J HansenJarad Martin
Jan 12, 2005·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·L LiviG P Biti
Jul 1, 2016·Archives of Pathology & Laboratory Medicine·Paula S GinterTimothy M D'Alfonso
Jul 11, 2018·Future Oncology·Jia-Yuan SunSan-Gang Wu
Sep 6, 2005·Breast Cancer Research and Treatment·Timothy SullivanAlphonse G Taghian
Sep 30, 2008·The Breast Journal·Timothy D WagnerGary Y Yang
Dec 6, 2017·Journal of Surgical Oncology·Éric PoirierLouise Provencher
Jun 15, 2018·Frontiers in Oncology·San-Gang WuZhen-Yu He
Nov 22, 2018·Radiation Oncology·Jian-Xian ChenSan-Gang Wu
Aug 26, 2021·The Breast Journal·Shahla Masood