Tubular carcinoma of the breast: further evidence to support its excellent prognosis

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
Emad A RakhaIan O Ellis

Abstract

PURPOSE Although tubular carcinoma (TC) is known to have a favorable prognosis, it is still unknown whether this subtype represents a distinct type of breast carcinoma or whether it behaves like other low-grade luminal A-type breast carcinomas. METHODS In this study, we performed a retrospective analysis of a large well-characterized series of breast cancers (2,608 carcinomas) to assess the clinicopathologic and molecular features and prognostic value of TC compared with grade 1 ductal carcinomas of the breast. Results When compared with grade 1 ductal carcinoma (n = 212), TC (n = 102) was more likely to be detected on mammographic screening, had smaller median size, and less frequently showed lymphovascular invasion. Compared with grade 1 ductal carcinoma, TC was associated with longer disease-free survival (chi(2) = 13.25, P < .001) and breast cancer-specific survival (chi(2) = 8.8, P = .003). In this study, none of the patients with TC developed distant metastasis or died from the disease without an intervening recurrence as invasive carcinoma of different histologic type. CONCLUSION We conclude that the biologic behavior of TC is excellent and is more favorable than that of grade 1 ductal carcinoma. Patients with TC may be ...Continue Reading

References

Aug 1, 1978·American Journal of Clinical Pathology·P H Carstens
Oct 1, 1977·Cancer·A S PatchefskyR E Nerlinger
Sep 1, 1989·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·P P RosenS Hellman
Mar 1, 1985·Histopathology·P H CarstensH Lyon
Sep 1, 1972·American Journal of Clinical Pathology·P H CarstensR Ashikari
Jul 1, 1982·American Journal of Clinical Pathology·P H Deos, H J Norris
Jul 1, 1982·The American Journal of Surgical Pathology·R W McDivittD Gersell
Aug 1, 1983·Human Pathology·F F Parl, L D Richardson
Jan 1, 1995·British Journal of Cancer·R Rajakariar, R A Walker
Mar 1, 1996·Annals of Surgery·D J WinchesterS E Singletary
Jun 1, 1997·The American Journal of Surgical Pathology·I GreenP P Rosen
May 20, 1999·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·S G DiabR M Elledge
Oct 26, 1999·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·J KolliasR W Blamey
Jun 3, 2000·Human Pathology·H Stalsberg, W H Hartmann
Jul 11, 2000·Archives of Pathology & Laboratory Medicine·P L FitzgibbonsS J Schnitt
Aug 17, 2000·British Journal of Cancer·T J AndersonA P Forrest
Feb 13, 2001·ANZ Journal of Surgery·P R KitchenJ P Collins
Mar 7, 2001·Human Pathology·F M WaldmanA Thor
May 12, 2001·The Breast Journal·Maria FasanoHelen Feiner
Sep 22, 2005·British Journal of Cancer·C I LiJ R Daling
Aug 26, 2006·The Breast : Official Journal of the European Society of Mastology·Sergio Fernandez-AguilarJean-Christophe Nöel
Sep 22, 2006·European Journal of Radiology·Işil Günhan-Bilgen, Ayşenur Oktay
Feb 27, 2007·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·R W BlameyC W Elston
Apr 11, 2007·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Hee Jung ShinGyungyub Gong
Feb 8, 2008·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·Sergio Fernandez-Aguilar, Jean-Christophe Noël
Apr 26, 2008·Virchows Archiv : an International Journal of Pathology·Gulisa TurashviliSamuel Aparicio
May 21, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Emad A RakhaIan O Ellis
Sep 16, 2008·American Journal of Surgery·Sara H JavidMehra Golshan

❮ Previous
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Citations

Dec 17, 2011·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Geza AcsChristine Laronga
Jun 8, 2013·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Geza AcsChristine Laronga
Nov 1, 2011·Annals of Oncology : Official Journal of the European Society for Medical Oncology·M ColleoniG Viale
May 2, 2012·Annals of Oncology : Official Journal of the European Society for Medical Oncology·H Bonnefoi, G MacGrogan
Oct 12, 2012·Molecular Biology Reports·Marla Karine AmaranteMaria Angelica Ehara Watanabe
Mar 13, 2010·Breast Cancer Research and Treatment·Aleksandra FilipovićR Charles Coombes
Oct 1, 2010·Annals of Surgical Oncology·Martin G FedkoJudy C Boughey
Mar 29, 2016·The Breast : Official Journal of the European Society of Mastology·Andrew EvansSarah J Vinnicombe
Nov 26, 2013·Clinics in Laboratory Medicine·Sudeshna Bandyopadhyay, Rouba Ali-Fehmi
Aug 7, 2013·Hematology/oncology Clinics of North America·Elisabetta MunzoneMarco Colleoni
Sep 1, 2012·Surgical Pathology Clinics·Timothy M D'Alfonso, Sandra J Shin
Jun 23, 2015·Histopathology·Emad A RakhaIan O Ellis
May 1, 2012·International Journal of Radiation Oncology, Biology, Physics·Baoqing LiSteven L Chen
Nov 2, 2011·The Breast : Official Journal of the European Society of Mastology·Marco ColleoniSilvia Dellapasqua
Aug 25, 2015·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Adele FrancisDaniel Rea
Feb 22, 2012·Journal of Medical Imaging and Radiation Oncology·Carmen J HansenJarad Martin
Mar 30, 2016·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·S StolnicuE Resetkova
Sep 21, 2015·Annals of Oncology : Official Journal of the European Society for Medical Oncology·E MunzoneUNKNOWN International Breast Cancer Study Group and the BIG 1-98 Collaborative Group
Jul 26, 2014·ANZ Journal of Surgery·Vivienne LeaDavid Gillett
May 11, 2010·Molecular Oncology·Britta WeigeltJorge S Reis-Filho
Jun 30, 2015·Bulletin du cancer·Camille FranchetMagali Lacroix-Triki
Feb 26, 2015·Journal of the National Cancer Institute·Charlotte K Y NgJorge S Reis-Filho
Sep 22, 2016·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·Vida PourteimoorMahdi Paryan
Feb 13, 2018·Pathobiology : Journal of Immunopathology, Molecular and Cellular Biology·Mohammed A AleskandaranyEmad A Rakha
Dec 26, 2017·Frontiers in Medicine·Gulisa Turashvili, Edi Brogi
Mar 13, 2018·Archives of Pathology & Laboratory Medicine·Scott KizyJane Yuet Ching Hui
Jul 11, 2018·Future Oncology·Jia-Yuan SunSan-Gang Wu
Aug 30, 2013·Expert Review of Anticancer Therapy·Louisa M GannonCecily M Quinn
Dec 23, 2017·Expert Review of Proteomics·Claudius MuellerVirginia Espina
Feb 11, 2020·Pathology International·Eric Ka Ho SheaPuay Hoon Tan
Jun 28, 2014·The Oncologist·Maria Vittoria DieciValentina Guarneri
May 28, 2020·The Breast Journal·Gulisa Turashvili, Hannah Y Wen

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