Tubular carcinoma of the breast. Predicting axillary nodal metastases and recurrence

Annals of Surgery
D J WinchesterS E Singletary

Abstract

Tubular carcinoma of the breast, a well-differentiated variant of infiltrating ductal carcinoma, has been regarded as a very favorable histologic subtype. The infrequency of nodal metastases and low recurrence rates have led to questions about the value of axillary dissection. The authors evaluated the frequency of axillary nodal metastases, the prognostic value of histologic features of the primary tumor, and treatment outcome in patients with tubular carcinoma of the breast. This retrospective analysis evaluated 50 patients who received diagnoses of tubular carcinoma from The University of Texas M. D. Anderson Cancer Center between 1944 and 1992. Medical records were reviewed for information about the patient, the tumor, treatment, and outcome. Hematoxylin-eosin stained sections were reviewed to confirm the diagnosis and assess histologic features. The median tumor diameter was 1.0 cm. Nine (20%) of 44 axilla had histologically confirmed lymph node involvement. Lymph node involvement was neither infrequent nor predicted by features of the primary tumor. Recurrences developed in 4 patients, and 1 patient died of tubular carcinoma. The 5-year disease-free survival rate was 88%. The local therapy used, mastectomy or breast prese...Continue Reading

References

Nov 1, 1978·Cancer·H S CooperR A Krall
Oct 1, 1979·The American Journal of Surgical Pathology·H A Oberman, W J Fidler
Aug 1, 1978·American Journal of Clinical Pathology·P H Carstens
Oct 1, 1977·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·D M BarnesL G Skinner
Feb 1, 1976·Acta Radiologica: Therapy, Physics, Biology·A WallgrenG Eklund
Jul 1, 1982·American Journal of Clinical Pathology·P H Deos, H J Norris
Feb 1, 1993·AJR. American Journal of Roentgenology·A J LeibmanB Kruse

❮ Previous
Next ❯

Citations

Sep 6, 2005·Breast Cancer Research and Treatment·Timothy SullivanAlphonse G Taghian
Aug 9, 2005·The Breast : Official Journal of the European Society of Mastology·Sergio Fernández-AguilarJean-Christophe Nöel
Apr 13, 2004·Clinical Oncology : a Journal of the Royal College of Radiologists·L J HamiltonK L Cheung
Jun 20, 2001·The British Journal of Surgery·G PapadatosJ Boyages
Feb 13, 2001·ANZ Journal of Surgery·P R KitchenJ P Collins
Nov 1, 2011·Annals of Oncology : Official Journal of the European Society for Medical Oncology·M ColleoniG Viale
Jan 24, 1998·The Australian and New Zealand Journal of Surgery·P R KitchenM A Henderson
Oct 1, 2010·Annals of Surgical Oncology·Martin G FedkoJudy C Boughey
Jan 11, 2000·AJR. American Journal of Roentgenology·D G SheppardC B Stelling
Dec 19, 2002·American Journal of Surgery·Sandra L WongUNKNOWN University of Louisville Breast Cancer Study Group
Sep 16, 2008·American Journal of Surgery·Sara H JavidMehra Golshan
Jul 9, 2003·The Breast Journal·Amadeo H CabralThomas W Mesko
Apr 20, 2004·International Journal of Radiation Oncology, Biology, Physics·Sarah A ThurmanAbram Recht
Nov 18, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Emad A RakhaIan O Ellis
Mar 20, 2002·Clinical Breast Cancer·D W HollandJ E Mortimer
Jul 26, 2014·ANZ Journal of Surgery·Vivienne LeaDavid Gillett
Apr 14, 2005·Annals of Surgical Oncology·Jane E MendezLisa M Sclafani
Jan 5, 2002·Journal of the National Cancer Institute. Monographs·M Morrow, H Krontiras
Dec 6, 2017·Journal of Surgical Oncology·Éric PoirierLouise Provencher
Sep 30, 2008·The Breast Journal·Timothy D WagnerGary Y Yang
Feb 22, 2012·Journal of Medical Imaging and Radiation Oncology·Carmen J HansenJarad Martin
Oct 21, 2020·Annals of Surgical Oncology·Enver ÖzkurtThanh U Barbie
May 18, 2021·Frontiers in Oncology·Jasna MetovicIsabella Castellano
Jun 27, 2021·The Breast Journal·Kai HuangEmmanuel M Gabriel

❮ Previous
Next ❯

Related Concepts

Related Feeds

Breast Invasive Carcinoma

Invasive breast cancers indicate a spread into breast tissues and lymph nodes. Here are the latest discoveries pertaining to breast invasive carcinomas.

Carcinoma, Ductal

Ductal carcinoma is a malignant neoplasm involving the ductal systems of any of a number of organs, such as the mammary glands, pancreas, prostate or lacrimal gland. Discover the latest research on ductal carcinoma here.

Breast Invasive Carcinoma (Keystone)

Invasive breast cancers indicate a spread into breast tissues and lymph nodes. Here are the latest discoveries pertaining to breast invasive carcinomas.