Tumescent anaesthesia: its applications and well tolerated use in the out-of-operating room setting

Current Opinion in Anaesthesiology
Natalie F Holt

Abstract

Tumescent anaesthesia is a method of administering dilute local anaesthetic into the subcutaneous tissue. Many anaesthesiologists are unfamiliar with the technique, its applications and potential risks. The maximum safe dose of lidocaine with epinephrine in tumescent anaesthesia for liposuction is probably between 35 and 55 mg/kg. Without liposuction, the maximum dose of lidocaine with epinephrine should be no more than 28 mg/kg. After tumescent infiltration for liposuction, serum lidocaine concentrations peak between 12 and 16 h after injection. When tumescent lidocaine without epinephrine is used for endovenous laser therapy, peak serum lidocaine concentrations are observed much earlier, between 1 and 2 h after injection. Slow administration of more dilute concentrations of local anaesthetic decreases the risk of local anaesthetic systemic toxicity. Although appealing because of its ability to provide prolonged analgesia, high doses of local anaesthetic are frequently administered using the tumescent technique, and absorption of local anaesthetic from the subcutaneous tissue is variable. When caring for patients having procedures in which tumescent anaesthesia is used, the risk of local anaesthetic toxicity should be acknowle...Continue Reading

References

Mar 1, 1990·The Journal of Dermatologic Surgery and Oncology·J A Klein
Oct 4, 1974·European Journal of Clinical Pharmacology·E KarlssonM D Rawlins
Feb 1, 1983·Clinical Pharmacology and Therapeutics·K A ConradL Burnham
Feb 1, 1983·Annals of Internal Medicine·A B KnappJ C Somberg
May 1, 1982·Annals of Internal Medicine·J FeelyA J Wood
Sep 1, 1995·Journal of the American Academy of Dermatology·S J SalascheN S Trookman
Nov 1, 1996·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·A OstadR L Moy
Apr 20, 1999·The American Journal of Forensic Medicine and Pathology·R H de Jong, F M Grazer
May 13, 1999·The New England Journal of Medicine·R B RaoR S Hoffman
Oct 20, 1999·Dermatologic Clinics·J A Klein
Nov 30, 1999·Plastic and Reconstructive Surgery·A W PerryM Rankin
Jan 8, 2000·Plastic and Reconstructive Surgery·F M Grazer, R H de Jong
Jan 8, 2000·Plastic and Reconstructive Surgery·S A Wolfe
Aug 10, 2001·Plastic and Reconstructive Surgery·A D ArmourM H Brown
Apr 2, 1960·Journal of the American Medical Association·F F FOLDESL R KOUKAL
Feb 26, 2005·The Breast Journal·Grant W Carlson
Mar 18, 2008·Forensic Science International : Synergy·María A MartínezManuel García
Apr 23, 2008·Surgical Infections·Svena M JohnsonAlan P Dine
Oct 1, 2007·The Canadian Journal of Plastic Surgery = Journal Canadien De Chirurgie Plastique·Michael Bell
Dec 8, 2009·Diseases of the Colon and Rectum·Cuneyt KayaalpTurgut Piskin
Feb 4, 2010·Seminars in Cutaneous Medicine and Surgery·Ryan William Ahern
Mar 11, 2010·Regional Anesthesia and Pain Medicine·Joseph M NealGuy L Weinberg
Apr 14, 2010·Journal of the European Academy of Dermatology and Venereology : JEADV·M D SchmittnerG C Beck
Sep 11, 2010·Plastic and Reconstructive Surgery·Phillip C HaeckUNKNOWN ASPS Patient Safety Committee
Mar 1, 2012·International Journal of Surgery·Georgios Galanopoulos, Constantinos Lambidis
Feb 5, 2013·The Surgeon : Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland·Patrick H Conroy, James O'Rourke
May 1, 2013·Plastic and Reconstructive Surgery·Meredith M PaceEmily B Ridgway
Dec 9, 2014·Annals of Surgical Treatment and Research·Ju Won ChyungYong Seog Jang
Jan 16, 2015·Annals of Plastic Surgery·Angie M PaikHenry C Hsia
Feb 20, 2016·Anesthesia and Analgesia·Jeffrey A Klein, Daniel R Jeske
Mar 10, 2016·Journal of the American Academy of Dermatology·David J KoubaJose V Moyano
Jan 1, 2015·Journal of Vascular Surgery. Venous and Lymphatic Disorders·Arlene J HudsonMercedes M Bailey

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Citations

Nov 19, 2020·The Western Journal of Emergency Medicine·Tim MontriefBrit J Long

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