Tumor detection with 1-aminocyclopentane and 1-aminocyclobutane C-11-carboxylic acid using positron emission computerized tomography

Clinical Nuclear Medicine
K F HübnerE C Holloway

Abstract

Eight patients with proven or suspected neoplastic lesions were examined with 1-aminocyclobutane C-11-carboxylic acid and 1-aminocyclopentane C-11-carboxylic acid using positron emission computed tomography. The results of this comparative study have shown that both of these unnatural amino acids have a high affinity for malignant tumors. The potential of nonmetabolizable C-11-labeled amino acids as noninvasive indicators of metabolic tumor activity is demonstrated and discussed.

Citations

Jan 1, 1984·European Journal of Nuclear Medicine·K KubotaK Ito
Sep 6, 2005·Amino Acids·R Bergmann, J Pietzsch
Dec 1, 2009·Amino Acids·Hao HongWeibo Cai
Oct 27, 2010·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·Bital Savir-BaruchMark M Goodman
Nov 1, 1982·The British Journal of Radiology·K SchelstraeteA De Schryver
Jul 28, 2011·Medicinal Research Reviews·Jonathan McConathyMark M Goodman
Mar 22, 2012·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Terry JonesUNKNOWN PET Research Advisory Company

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cancer Metabolism

In order for cancer cells to maintain rapid, uncontrolled cell proliferation, they must acquire a source of energy. Cancer cells acquire metabolic energy from their surrounding environment and utilize the host cell nutrients to do so. Here is the latest research on cancer metabolism.