PMID: 16613314Apr 15, 2006Paper

Tumor extension in high-grade gliomas assessed with diffusion magnetic resonance imaging: values and lesion-to-brain ratios of apparent diffusion coefficient and fractional anisotropy

Acta Radiologica
D van WestenE M Larsson

Abstract

To determine whether the apparent diffusion coefficient (ADC) and fractional anisotropy (FA) can distinguish tumor-infiltrated edema in gliomas from pure edema in meningiomas and metastases. Thirty patients were studied: 18 WHO grade III or IV gliomas, 7 meningiomas, and 5 metastatic lesions. ADC and FA were determined from ROIs placed in peritumoral areas with T2-signal changes, adjacent normal appearing white matter (NAWM), and corresponding areas in the contralateral healthy brain. Values and lesion-to-brain ratios from gliomas were compared to those from meningiomas and metastases. Values and lesion-to-brain ratios of ADC and FA in peritumoral areas with T2-signal changes did not differ between gliomas, meningiomas, and metastases (P = 0.40, P = 0.40, P = 0.61, P = 0.34). Values of ADC and FA and the lesion-to-brain ratio of FA in the adjacent NAWM did not differ between tumor types (P = 0.74, P = 0.25, and P = 0.31). The lesion-to-brain ratio of ADC in the adjacent NAWM was higher in gliomas than in meningiomas and metastases (P = 0.004), but overlapped between tumor types. Values and lesion-to-brain ratios of ADC and FA in areas with T2-signal changes surrounding intracranial tumors and adjacent NAWM were not helpful for ...Continue Reading

References

Jan 1, 1992·Neuroradiology·M WatanabeN Takeda
Jun 1, 1987·Journal of Neurosurgery·P J KellyJ J Illig
Mar 1, 1994·Journal of Magnetic Resonance. Series B·P J BasserD LeBihan
Aug 1, 1996·Neurosurgery·A Giese, M Westphal
Dec 1, 1996·Radiology·C PierpaoliG Di Chiro
Dec 1, 1996·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·C Pierpaoli, P J Basser
Jul 1, 1997·Neuroradiology·K KrabbeF Madsen
May 18, 2001·Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society·R N Sener
Jul 20, 2001·AJR. American Journal of Roentgenology·K M GauvainR J Hayashi
Aug 2, 2002·Neuroreport·Mark E BastinJoanna M Wardlaw
Oct 19, 2004·Journal of Neurology, Neurosurgery, and Psychiatry·S SinhaI R Whittle
Nov 24, 2004·Journal of Magnetic Resonance Imaging : JMRI·A TropineP Stoeter

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Citations

Dec 17, 2008·La Radiologia medica·T ScarabinoU Salvolini
Apr 1, 2009·Nature Reviews. Clinical Oncology·Elizabeth R GerstnerTracy T Batchelor
Jan 8, 2014·Journal of Magnetic Resonance Imaging : JMRI·Christophe VandendriesGuillaume Saliou
Oct 20, 2012·Acta Radiologica·Eun Kyoung LeeYong Seok Lee
Dec 12, 2007·British Journal of Neurosurgery·Stephen J Price
May 16, 2014·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Jatta BerberatSusanne Rogers
Dec 10, 2015·Journal of Intensive Care Medicine·Yoshua EsquenaziKiwon Lee
Sep 10, 2016·Radiology Research and Practice·Yan ZhangXuelin Zhang
May 25, 2012·The British Journal of Radiology·S J Price, J H Gillard
Jan 23, 2015·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Patricia SvolosIoannis Tsougos
Oct 1, 2016·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Kimberly L DesmondGreg J Stanisz
Jan 9, 2021·The Neuroradiology Journal·Sanaz Beig ZaliMasoud Poureisa

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